Selenocompounds in cancer therapy: an overview
In vitro and in vivo experimental models clearly demonstrate the efficacy of Se compounds
as anticancer agents, contingent upon chemical structures and concentrations of test …
as anticancer agents, contingent upon chemical structures and concentrations of test …
[HTML][HTML] Organic selenium compounds as potential chemotherapeutic agents for improved cancer treatment
V Gandin, P Khalkar, J Braude… - Free Radical Biology and …, 2018 - Elsevier
Selenium (Se)-containing compounds have attracted a growing interest as anticancer
agents over recent decades, with mounting reports demonstrating their high efficacy and …
agents over recent decades, with mounting reports demonstrating their high efficacy and …
Redox-active selenium compounds—From toxicity and cell death to cancer treatment
Selenium is generally known as an antioxidant due to its presence in selenoproteins as
selenocysteine, but it is also toxic. The toxic effects of selenium are, however, strictly …
selenocysteine, but it is also toxic. The toxic effects of selenium are, however, strictly …
Selenium-containing agents acting on cancer—a new hope?
S Garbo, S Di Giacomo, D Łażewska… - Pharmaceutics, 2022 - mdpi.com
Selenium-containing agents are more and more considered as an innovative potential
treatment option for cancer. Light is shed not only on the considerable advancements made …
treatment option for cancer. Light is shed not only on the considerable advancements made …
Selenium compounds and selenoproteins in cancer
R Brigelius‐Flohé - Chemistry & biodiversity, 2008 - Wiley Online Library
An adequate selenium (Se) status has for long been considered to prevent the development
of various forms of cancer. However, underlying molecular mechanisms remained unknown …
of various forms of cancer. However, underlying molecular mechanisms remained unknown …
Selenium compounds as therapeutic agents in cancer
AP Fernandes, V Gandin - Biochimica et Biophysica Acta (BBA)-General …, 2015 - Elsevier
Background With cancer cells encompassing consistently higher production of reactive
oxygen species (ROS) and with an induced antioxidant defense to counteract the increased …
oxygen species (ROS) and with an induced antioxidant defense to counteract the increased …
Optimising selenium for modulation of cancer treatments
SO Evans, PF Khairuddin, MB Jameson - Anticancer research, 2017 - ar.iiarjournals.org
Selenium is an essential trace element involved in many biological processes that are
mediated through, at least, 25 selenoproteins expressed in humans. Extensive study of …
mediated through, at least, 25 selenoproteins expressed in humans. Extensive study of …
Selenium compounds as novel potential anticancer agents
D Radomska, R Czarnomysy, D Radomski… - International Journal of …, 2021 - mdpi.com
The high number of new cancer incidences and the associated mortality continue to be
alarming, leading to the search for new therapies that would be more effective and less …
alarming, leading to the search for new therapies that would be more effective and less …
Aspects of a distinct cytotoxicity of selenium salts and organic selenides in living cells with possible implications for drug design
E Castellucci Estevam, K Witek, L Faulstich, MJ Nasim… - Molecules, 2015 - mdpi.com
Selenium is traditionally considered as an antioxidant element and selenium compounds
are often discussed in the context of chemoprevention and therapy. Recent studies …
are often discussed in the context of chemoprevention and therapy. Recent studies …
[图书][B] Organoselenium compounds in biology and medicine: synthesis, biological and therapeutic treatments
VK Jain, KI Priyadarsini - 2017 - books.google.com
Organoselenium shows incredible promise in medicine, particularly cancer therapy. This
book discusses organoselenium chemistry and biology in the context of its therapeutic …
book discusses organoselenium chemistry and biology in the context of its therapeutic …