Selenocompounds in cancer therapy: an overview

D Bartolini, L Sancineto, AF de Bem, KD Tew… - Advances in Cancer …, 2017 - Elsevier
In vitro and in vivo experimental models clearly demonstrate the efficacy of Se compounds
as anticancer agents, contingent upon chemical structures and concentrations of test …

[HTML][HTML] Organic selenium compounds as potential chemotherapeutic agents for improved cancer treatment

V Gandin, P Khalkar, J Braude… - Free Radical Biology and …, 2018 - Elsevier
Selenium (Se)-containing compounds have attracted a growing interest as anticancer
agents over recent decades, with mounting reports demonstrating their high efficacy and …

Redox-active selenium compounds—From toxicity and cell death to cancer treatment

S Misra, M Boylan, A Selvam, JE Spallholz… - Nutrients, 2015 - mdpi.com
Selenium is generally known as an antioxidant due to its presence in selenoproteins as
selenocysteine, but it is also toxic. The toxic effects of selenium are, however, strictly …

Selenium-containing agents acting on cancer—a new hope?

S Garbo, S Di Giacomo, D Łażewska… - Pharmaceutics, 2022 - mdpi.com
Selenium-containing agents are more and more considered as an innovative potential
treatment option for cancer. Light is shed not only on the considerable advancements made …

Selenium compounds and selenoproteins in cancer

R Brigelius‐Flohé - Chemistry & biodiversity, 2008 - Wiley Online Library
An adequate selenium (Se) status has for long been considered to prevent the development
of various forms of cancer. However, underlying molecular mechanisms remained unknown …

Selenium compounds as therapeutic agents in cancer

AP Fernandes, V Gandin - Biochimica et Biophysica Acta (BBA)-General …, 2015 - Elsevier
Background With cancer cells encompassing consistently higher production of reactive
oxygen species (ROS) and with an induced antioxidant defense to counteract the increased …

Optimising selenium for modulation of cancer treatments

SO Evans, PF Khairuddin, MB Jameson - Anticancer research, 2017 - ar.iiarjournals.org
Selenium is an essential trace element involved in many biological processes that are
mediated through, at least, 25 selenoproteins expressed in humans. Extensive study of …

Selenium compounds as novel potential anticancer agents

D Radomska, R Czarnomysy, D Radomski… - International Journal of …, 2021 - mdpi.com
The high number of new cancer incidences and the associated mortality continue to be
alarming, leading to the search for new therapies that would be more effective and less …

Aspects of a distinct cytotoxicity of selenium salts and organic selenides in living cells with possible implications for drug design

E Castellucci Estevam, K Witek, L Faulstich, MJ Nasim… - Molecules, 2015 - mdpi.com
Selenium is traditionally considered as an antioxidant element and selenium compounds
are often discussed in the context of chemoprevention and therapy. Recent studies …

[图书][B] Organoselenium compounds in biology and medicine: synthesis, biological and therapeutic treatments

VK Jain, KI Priyadarsini - 2017 - books.google.com
Organoselenium shows incredible promise in medicine, particularly cancer therapy. This
book discusses organoselenium chemistry and biology in the context of its therapeutic …