A proposed diagnostic approach for infantile spasms based on a spectrum of variable aetiology

AL Poulat, G Lesca, D Sanlaville, G Blanchard… - European Journal of …, 2014 - Elsevier
Aim To identify the aetiology of patients with infantile spasms and propose practical
guidelines for diagnostic strategies. Method We performed a retrospective study of children …

Brain MRI findings in infantile spasm: outcome correlations in a patient cohort

A Khatami, E Sell, M Aggag… - Open Journal of …, 2016 - eprints.go4mailburst.com
Background: Infantile spasm is a type of pediatric seizure often associated with a negative
prognosis. The aim of this study was to evaluate the role of Magnetic Resonance Imaging …

The underlying etiology of infantile spasms (West syndrome): Information from the United Kingdom Infantile Spasms Study (UKISS) on contemporary causes and their …

JP Osborne, AL Lux, SW Edwards, E Hancock… - …, 2010 - Wiley Online Library
Purpose: To examine the underlying etiology of infantile spasms from the United Kingdom
Infantile Spasms Study (UKISS), using the pediatric adaptation of ICD 10. Methods: Infants …

Detailed magnetic resonance imaging (MRI) analysis in infantile spasms

C Harini, S Sharda, AM Bergin… - Journal of child …, 2018 - journals.sagepub.com
Purpose: To evaluate initial magnetic resonance imaging (MRI) abnormalities in infantile
spasms, correlate them to clinical characteristics, and describe repeat imaging findings …

Infantile spasms: West syndrome

L Carmant - Archives of neurology, 2002 - jamanetwork.com
West syndrome is an epileptic syndrome with a devastating clinical course. In recent years,
anatomic and functional neuroimaging studies have helped to diagnose the cause of the …

Infantile spasms: assessing the diagnostic yield of an institutional guideline and the impact of etiology on long‐term treatment response

N Chourasia, CJ Yuskaitis, MH Libenson… - …, 2022 - Wiley Online Library
Objective Neuroimaging and genetic testing have been proposed for diagnostic evaluation
of infantile spasms (IS), establishing etiology in~ 60% of multicenter IS cohorts. A …

Neurodevelopmental evolution of West syndrome: a 2-year prospective study

F Guzzetta, G Cioni, E Mercuri, E Fazzi… - European Journal of …, 2008 - Elsevier
OBJECTIVE: The aim of this study was to evaluate the epileptic and developmental
evolution in infants with West syndrome. METHODS: A prospective study of 21 infants was …

Definitions and diagnostic criteria for infantile spasms and west syndrome–historical perspectives and practical considerations

JR Mytinger - Seminars in Pediatric Neurology, 2021 - Elsevier
The term infantile spasms has been used inconsistently within the medical literature for
decades. We are also without formal consensus on the diagnostic criteria for West …

Infantile spasms: A proposal for a staged evaluation

JV Trasmonte, TF Barron - Pediatric neurology, 1998 - Elsevier
The purpose of this study was to determine whether a staged, algorithmic evaluation of
infantile spasms could be developed to minimize patient discomfort, treatment delay, and …

Cerebral blood flow abnormalities in symptomatic West syndrome: a single photon emission computed tomography study

U Karagöl, G Deda, S Uysal, N Kabakus… - Pediatrics …, 2001 - Wiley Online Library
Background: Infantile spasm (IS) is an age‐dependent epileptic encephalopathy of variable
etiology. Although IS is well studied, its pathogenesis is unclear. Infantile spasm is usually …