Advancements in human genetics now poise the field to illuminate the pathophysiology of
complex genetic disease. In particular, genome-wide association studies (GWAS) have …

The major inflammatory bowel diseases, Crohn's disease and ulcerative colitis, are both
debilitating disorders of the gastrointestinal tract, characterized by a dysregulated immune …

We are currently in an exciting time when our understanding of genetic underpinnings of
inflammatory bowel disease (IBD) has undergone a revolution, based in large part on novel …

Inflammatory bowel disease (IBD) is a destructive, recurrent, and heterogeneous disease. Its
detailed pathogenesis is still unclear, although available evidence supports that IBD is …

Inflammatory bowel diseases (IBDs) are complex, multifactorial disorders characterized by
chronic relapsing intestinal inflammation. Although etiology remains largely unknown, recent …

Crohn's disease (CD) and ulcerative colitis (UC), also known as inflammatory bowel
diseases (IBD), are characterized by chronic inflammation of the gastrointestinal tract. IBD is …

In this review, we provide an update on genome-wide association studies (GWAS) in
inflammatory bowel disease (IBD). In addition, we summarize progress in defining the …

Inflammatory bowel diseases (IBD) comprise a distinct set of clinical symptoms resulting
from chronic or relapsing immune activation and corresponding inflammation within the …

Inflammatory bowel disease (IBD) is a complex genetic disease that is instigated and
amplified by the confluence of multiple genetic and environmental variables that perturb the …

Epidemiological and clinical studies have suggested that the pathogenesis of inflammatory
bowel disease (IBD) is strongly influenced by genetic predisposition. Beyond the limitations …