Cloning and characterization of murine Aqp5: evidence for a conserved aquaporin gene cluster

CM Krane, JE Towne, AG Menon - Mammalian Genome, 1999 - Springer
Aquaporin 5 (Aqp5), a member of the aquaporin family of membrane water channels, is
thought to modulate the osmolality of fluids in the eye, lung, and salivary gland. Here, we …

More than just water channels: unexpected cellular roles of aquaporins

AS Verkman - Journal of cell science, 2005 - journals.biologists.com
Aquaporins (AQPs) are membrane proteins that transport water and, in some cases, also
small solutes such as glycerol. AQPs are expressed in many fluid-transporting tissues, such …

Cellular distribution of the aquaporins: a family of water channel proteins

D Brown, T Katsura, M Kawashima… - Histochemistry and cell …, 1995 - Springer
A group of transmembrane proteins that are related to the major intrinsic protein of lens
fibers (MIP26) have been named “aquaporins” to reflect their role as water channels. These …

How water molecules pass through aquaporins

T Zeuthen - Trends in biochemical sciences, 2001 - cell.com
The discovery of a family of water channels, the aquaporins (AQPs), has shown that
membrane proteins constitute a major pathway for water transport. The recent determination …

Aquaporins in urinary system

Y Li, W Wang, T Jiang, B Yang - Aquaporins, 2017 - Springer
Several aquaporin (AQP)-type water channels are expressed in kidney: AQP1 in the
proximal tubule, thin descending limb of Henle, and vasa recta; AQP2-6 in the collecting …

The aquaporins. A family of water channel proteins

DL Connolly, CM Shanahan, PL Weissberg - The international journal of …, 1998 - Elsevier
The recent discovery of aquaporins, a family of highly conserved water channel proteins,
which are expressed in both eukaryotes and prokaryotes, has provoked a re-evaluation of …

Cloning and functional expression of a new water channel abundantly expressed in the testis permeable to water, glycerol, and urea

K Ishibashi, M Kuwahara, Y Gu, Y Kageyama… - Journal of Biological …, 1997 - ASBMB
A new member of the aquaporin (AQP) family has been identified from rat testis. This gene,
referred as aquaporin 7 (AQP7), encodes a 269-amino acid protein that contained the …

Aquaporin-6: An intracellular vesicle water channel protein in renal epithelia

M Yasui, TH Kwon, MA Knepper… - Proceedings of the …, 1999 - National Acad Sciences
All characterized mammalian aquaporins (AQPs) are localized to plasma membranes where
they function chiefly to mediate water transport across cells. Here we show that AQP6 is …

High-resolution x-ray structure of human aquaporin 5

R Horsefield, K Nordén, M Fellert… - Proceedings of the …, 2008 - National Acad Sciences
Human aquaporin 5 (HsAQP5) facilitates the transport of water across plasma membranes
and has been identified within cells of the stomach, duodenum, pancreas, airways, lungs …

Purification and functional characterization of aquaporin‐8

K Liu, H Nagase, CG Huang, G Calamita… - Biology of the …, 2006 - Wiley Online Library
Background information. Aquaporins (AQPs) are a family of channels permeable to water
and some small solutes. In mammals, 13 members (AQP0–AQP12) have been found. AQP8 …