[HTML][HTML] A Biochemical and Pharmacological Characterization of Phospholipase A2 and Metalloproteinase Fractions from Eastern Russell's Viper (Daboia siamensis …

J Chaisakul, O Khow, K Wiwatwarayos, MRA Rusmili… - Toxins, 2021 - mdpi.com
Acute kidney injury (AKI) following Eastern Russell's viper (Daboia siamensis) envenoming
is a significant symptom in systemically envenomed victims. A number of venom …

Effects of phospholipase A2 and metalloprotease fractions of Russell's viper venom on cytokines and renal hemodynamics in dogs

C Mitrmoonpitak, P Chulasugandha, O Khow… - Toxicon, 2013 - Elsevier
Several enzymes in Russell's viper (Daboia siamensis) venom are involved in the venom
effects and renal injury. The effects of fractional components of Russell's viper venom …

Identification and characterization of a phospholipase A2 from the venom of the Saw-scaled viper: Novel bactericidal and membrane damaging activities

RP Samy, P Gopalakrishnakone, H Bow, PN Puspharaj… - Biochimie, 2010 - Elsevier
Phospholipase A2 (PLA2), a common toxic component of snake venom, has been
implicated in various pharmacological effects. In this study, a basic myotoxic PLA2, named …

Biochemical and pharmacological characterization of three toxic phospholipase A2s from Daboia russelii snake venom

JR Kumar, BS Basavarajappa, BS Vishwanath… - … and Physiology Part C …, 2015 - Elsevier
Three isoenzymes of phospholipase A 2 (PLA 2), VRV-PL-IIIc, VRV-PL-VII, and VRV-PL-IX
were isolated from Daboia russelii snake venom. The venom, upon gel filtration on …

In vivo treatment with varespladib, a phospholipase A2 inhibitor, prevents the peripheral neurotoxicity and systemic disorders induced by Micrurus corallinus (coral …

R Silva-Carvalho, MZ Gaspar, LHB Quadros… - Toxicology Letters, 2022 - Elsevier
In this study, we investigated the action of varespladib (VPL) alone or in combination with a
coral snake antivenom (CAV) on the local and systemic effects induced by Micrurus …

[HTML][HTML] The pathophysiological effects of Russell's viper (Daboia siamensis) venom and its fractions in the isolated perfused rabbit kidney model: A potential role for …

N Chaiyabutr, L Chanhome, T Vasaruchapong… - Toxicon: X, 2020 - Elsevier
Highlights•We investigated the effect of Russell's viper venom on the isolated perfused
kidney.•The renal effects of venom and its fractions mediated via platelet activating …

[HTML][HTML] Cytotoxic and inflammatory potential of a phospholipase A2 from Bothrops jararaca snake venom

RCA Cedro, DL Menaldo, TR Costa… - Journal of Venomous …, 2018 - SciELO Brasil
Background: Snake venom phospholipases A2 (PLA2s) have been reported to induce
myotoxic, neurotoxic, hemolytic, edematogenic, cytotoxic and proinflammatory effects. This …

[HTML][HTML] Molecular cloning and biochemical characterization of a myotoxin inhibitor from Bothrops alternatus snake plasma

NA Santos-Filho, CAH Fernandes, DL Menaldo… - Biochimie, 2011 - Elsevier
Phospholipases A2 (PLA2s) are important components of Bothrops snake venoms, that can
induce several effects on envenomations such as myotoxicity, inhibition or induction of …

[PDF][PDF] Molecular Cloning of PhospholipaseA2 from a Thai Russell's Viper Venom.. Gland cDNA Library

L CHANHOME - J Med Assoc Thai, 2001 - lymfiru.research.chula.ac.th
Snake venom contains several toxins. Russell's viper (D. russellii, RV) is a venomous snake
prevalent in northcm and central Thailand. RV bites can cause disseminated coagulation …

Isolation and functional characterization of a new myotoxic acidic phospholipase A2 from Bothrops pauloensis snake venom

RS Rodrigues, LFM Izidoro, SS Teixeira, LB Silveira… - Toxicon, 2007 - Elsevier
This article reports the purification procedure and the biochemical/functional
characterization of Bp-PLA2, a new myotoxic acidic phospholipase A2 from Bothrops …