Candidiasis is considered an emerging public health concern because of the occurrence of
drug-resistant Candida strains and the lack of an available structurally diverse antifungal …

Vaginal candidiasis is a medical condition characterized by the overgrowth of Candida spp.
in the vaginal cavity with complex recurrent pathogenicity as well as tolerance to antifungal …

Considering the escalating resistance to conventional antifungal medications, it is critical to
identify novel compounds that can efficiently counteract this challenge. The purpose of this …

Highlights What are the main findings? Baicalein-Core Derivatives were designed and
synthesized as Potent Anti-Fluconazole-resistant fungal Agents. O-dihydroxyls and vic …

Candida albicans CNB1 plays a role in the response in vitro and in vivo to stress generated
by PB-WUT-01, namely 1, 3-dimethyl-7-(2-((1-(3-(perbromo-2H-benzo [d][1, 2, 3] triazol-2-yl) …

Demand has arisen for developing new azole antifungal agents with the growth of the
resistant rate of infective fungal species to current azole antifungals in recent years …

Cryptococcosis is a fungal infection caused mainly by the pathogenic yeasts Cryptococcus
neoformans and Cryptococcus gattii. The infection initiates with the inhalation of propagules …

Cryptococcus neoformans (C. neoformans) and Candida albicans (C. albicans) are
classified as the critical priority groups among the pathogenic fungi, highlighting the urgent …

Glochidioboside was obtained from Sambucus williamsii and its biological effect has not
been reported. Its antifungal activity against pathogenic fungi and the mode of action …

Candida auris, a pathogenic fungus, has posed significant challenges to conventional
medical treatments due to its increasing resistance to antifungal agents. Consequently, due …