It was previously shown that more than half of the human oocytes obtained from IVF patients
of advanced reproductive age are aneuploid, due to meiosis I and meiosis II errors. The …

BACKGROUND The development competence of human oocytes declines with increasing
age. The objective of this study was to investigate the effect of age on gene expression …

OBJECTIVE: Controlled ovarian hyperstimulation yields numerous oocytes with different
morphologic features. The purpose of this study was to assess the effect of oocyte …

Purpose: To date, the impact of oocyte maturity at aspiration on the blastocyst formation in
vitro has not been fully evaluated. This study was undertaken to assess the influence of …

Infertility is described as unexplained when pregnancy does not occur despite ovulation,
patent Fallopian tubes, and normal semen parameters. Oocyte developmental competence …

Oocytes play a pivotal role in the cycle of human life. As we discuss here, after emerging
from germline stem cells in the fetus, they grow in a follicular niche in which development is …

Metaphase II-stage oocytes collected from patients following ovarian stimulation show
varying qualities. Both nuclear and cytoplasmic maturation have to be completed in a co …

The age‐associated decline in female fertility is largely ascribable to a decrease in oocyte
quality. This phenomenon is multifaceted and influenced by numerous interconnected …

The identification of genes and deduced pathways from the mature human oocyte can help
us better understand oogenesis, folliculogenesis, fertilization, and embryonic development …

Besides the established selection criteria based on embryo morphology and blastomere
number, new parameters for embryo viability are needed to improve the clinical outcome of …