Identification of differentially expressed markers in human follicular cells associated with competent oocytes
M Hamel, I Dufort, C Robert, C Gravel… - Human …, 2008 - academic.oup.com
BACKGROUND The development of an accurate method for selection of high-quality
embryos is essential to achieve high pregnancy rates with single embryo transfer in human …
embryos is essential to achieve high pregnancy rates with single embryo transfer in human …
[HTML][HTML] RUNX2, GPX3 and PTX3 gene expression profiling in cumulus cells are reflective oocyte/embryo competence and potentially reliable predictors of embryo …
X Huang, C Hao, X Shen, Y Zhang, X Liu - Reproductive Biology and …, 2013 - Springer
Background Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic
disorder in women. The developmental competence of oocytes and embryos in PCOS …
disorder in women. The developmental competence of oocytes and embryos in PCOS …
The dormant and the fully competent oocyte: comparing the transcriptome of human oocytes from primordial follicles and in metaphase II
ML Grøndahl, R Borup, J Vikeså, E Ernst… - MHR: Basic science …, 2013 - academic.oup.com
Oocytes become enclosed in primordial follicles during fetal life and remain dormant there
until activation followed by growth and meiotic resumption. Current knowledge about the …
until activation followed by growth and meiotic resumption. Current knowledge about the …
Origins and mechanisms leading to aneuploidy in human eggs
L Wartosch, K Schindler, M Schuh, JR Gruhn… - Prenatal …, 2021 - Wiley Online Library
The gain or loss of a chromosome—or aneuploidy—acts as one of the major triggers for
infertility and pregnancy loss in humans. These chromosomal abnormalities affect more than …
infertility and pregnancy loss in humans. These chromosomal abnormalities affect more than …
Tracking of oocyte dysmorphisms for ICSI patients may prove relevant to the outcome in subsequent patient cycles
JS Meriano, J Alexis, S Visram-Zaver… - Human …, 2001 - academic.oup.com
BACKGROUND: We determined whether oocyte dysmorphisms, especially repetition of
specific dysmorphisms from cycle to cycle, had a prognostic impact on intracytoplasmic …
specific dysmorphisms from cycle to cycle, had a prognostic impact on intracytoplasmic …
An integrated investigation of oocyte developmental competence: expression of key genes in human cumulus cells, morphokinetics of early divisions, blastulation, and …
C Scarica, D Cimadomo, L Dovere, A Giancani… - Journal of assisted …, 2019 - Springer
Purpose To investigate the association of cumulus cell (CC)-related expression of a selected
cluster of key genes (PTGS2, CAMK1D, HAS2, STC1, and EFNB2) with embryo …
cluster of key genes (PTGS2, CAMK1D, HAS2, STC1, and EFNB2) with embryo …
Human oocyte maturation in vitro is improved by co-culture with cumulus cells from mature oocytes
I Virant-Klun, C Bauer, A Ståhlberg, M Kubista… - Reproductive …, 2018 - Elsevier
The conventional method of human oocyte maturation in vitro in the presence of
gonadotrophins continues to be a relatively low-success procedure in the assisted …
gonadotrophins continues to be a relatively low-success procedure in the assisted …
In vitro maturation (IVM) of oocytes in patients with resistant ovary syndrome and in patients with repeated deficient oocyte maturation
A Galvao, I Segers, J Smitz, H Tournaye… - Journal of assisted …, 2018 - Springer
Purpose To assess the efficiency of IVM in patients with repeated ART failure due to
resistant ovary syndrome or due to deficient oocyte maturation. Methods Clinical and …
resistant ovary syndrome or due to deficient oocyte maturation. Methods Clinical and …
Testing for genetic contributions to infertility: potential clinical impact
C Krausz, F Cioppi… - Expert review of molecular …, 2018 - Taylor & Francis
Introduction: Male infertility affects about 7% of the general male population, and it is a
multifactorial, polygenic pathological condition. Known genetic factors, accounting for about …
multifactorial, polygenic pathological condition. Known genetic factors, accounting for about …
[HTML][HTML] Impeding DNA break repair enables oocyte quality control
Oocyte quality control culls eggs with defects in meiosis. In mouse, oocyte death can be
triggered by defects in chromosome synapsis and recombination, which involve repair of …
triggered by defects in chromosome synapsis and recombination, which involve repair of …