Identification of differentially expressed markers in human follicular cells associated with competent oocytes

M Hamel, I Dufort, C Robert, C Gravel… - Human …, 2008 - academic.oup.com
BACKGROUND The development of an accurate method for selection of high-quality
embryos is essential to achieve high pregnancy rates with single embryo transfer in human …

[HTML][HTML] RUNX2, GPX3 and PTX3 gene expression profiling in cumulus cells are reflective oocyte/embryo competence and potentially reliable predictors of embryo …

X Huang, C Hao, X Shen, Y Zhang, X Liu - Reproductive Biology and …, 2013 - Springer
Background Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic
disorder in women. The developmental competence of oocytes and embryos in PCOS …

The dormant and the fully competent oocyte: comparing the transcriptome of human oocytes from primordial follicles and in metaphase II

ML Grøndahl, R Borup, J Vikeså, E Ernst… - MHR: Basic science …, 2013 - academic.oup.com
Oocytes become enclosed in primordial follicles during fetal life and remain dormant there
until activation followed by growth and meiotic resumption. Current knowledge about the …

Origins and mechanisms leading to aneuploidy in human eggs

L Wartosch, K Schindler, M Schuh, JR Gruhn… - Prenatal …, 2021 - Wiley Online Library
The gain or loss of a chromosome—or aneuploidy—acts as one of the major triggers for
infertility and pregnancy loss in humans. These chromosomal abnormalities affect more than …

Tracking of oocyte dysmorphisms for ICSI patients may prove relevant to the outcome in subsequent patient cycles

JS Meriano, J Alexis, S Visram-Zaver… - Human …, 2001 - academic.oup.com
BACKGROUND: We determined whether oocyte dysmorphisms, especially repetition of
specific dysmorphisms from cycle to cycle, had a prognostic impact on intracytoplasmic …

An integrated investigation of oocyte developmental competence: expression of key genes in human cumulus cells, morphokinetics of early divisions, blastulation, and …

C Scarica, D Cimadomo, L Dovere, A Giancani… - Journal of assisted …, 2019 - Springer
Purpose To investigate the association of cumulus cell (CC)-related expression of a selected
cluster of key genes (PTGS2, CAMK1D, HAS2, STC1, and EFNB2) with embryo …

Human oocyte maturation in vitro is improved by co-culture with cumulus cells from mature oocytes

I Virant-Klun, C Bauer, A Ståhlberg, M Kubista… - Reproductive …, 2018 - Elsevier
The conventional method of human oocyte maturation in vitro in the presence of
gonadotrophins continues to be a relatively low-success procedure in the assisted …

In vitro maturation (IVM) of oocytes in patients with resistant ovary syndrome and in patients with repeated deficient oocyte maturation

A Galvao, I Segers, J Smitz, H Tournaye… - Journal of assisted …, 2018 - Springer
Purpose To assess the efficiency of IVM in patients with repeated ART failure due to
resistant ovary syndrome or due to deficient oocyte maturation. Methods Clinical and …

Testing for genetic contributions to infertility: potential clinical impact

C Krausz, F Cioppi… - Expert review of molecular …, 2018 - Taylor & Francis
Introduction: Male infertility affects about 7% of the general male population, and it is a
multifactorial, polygenic pathological condition. Known genetic factors, accounting for about …

[HTML][HTML] Impeding DNA break repair enables oocyte quality control

H Qiao, HBDP Rao, Y Yun, S Sandhu, JH Fong… - Molecular cell, 2018 - cell.com
Oocyte quality control culls eggs with defects in meiosis. In mouse, oocyte death can be
triggered by defects in chromosome synapsis and recombination, which involve repair of …