FISH analysis for chromosomes 13, 16, 18, 21, 22, X and Y in all blastomeres of IVF pre‐embryos from 144 randomly selected donated human oocytes and impact on …

S Ziebe, K Lundin, A Loft, C Bergh… - Human …, 2003 - academic.oup.com
BACKGROUND: The data are compiled from two multicentre, prospectively randomized
studies on the effect of follicular fluid meiosis‐activating sterol (FF‐MAS) on human oocytes …

Revisiting oocyte–somatic cell interactions: in search of novel intrafollicular predictors and regulators of oocyte developmental competence

Q Li, LJ McKenzie, MM Matzuk - Molecular human reproduction, 2008 - academic.oup.com
Prediction and improvement of oocyte competence are two critical issues in assisted
reproductive technology to improve infertility therapy. The lack of reliable and objective …

Developmental failure in human reproduction associated with preovulatory oogenesis and preimplantation embryogenesis

J Van Blerkom - Ultrastructure of human gametogenesis and early …, 1989 - Springer
The rapid and worldwide application of in vitro fertilization (IVF) for the treatment of human
infertility has presented the opportunity to examine, by noninvasive (1) and invasive …

Cytogenetics of uncleaved oocytes and arrested zygotes in IVF programs

M Benkhalifa, Y Menezo, L Janny, JL Pouly… - Journal of assisted …, 1996 - Springer
Purpose: Cytogenetic studies of arrested oocytes and zygotes were used to understand in
vitro fertilization (IVF) failures. Methods: We investigated the cytogenetics (Giemsa banding …

[HTML][HTML] Diminished ovarian reserve is associated with reduced euploid rates via preimplantation genetic testing for aneuploidy independently from age: evidence for …

EG Jaswa, CE McCulloch, R Simbulan, MI Cedars… - Fertility and sterility, 2021 - Elsevier
Objective (s) To determine whether women with diminished ovarian reserve
(DOR)(quantitatively) had lower rates of euploid blastocysts, as a proxy for oocyte quality …

[HTML][HTML] Biallelic mutations in PATL2 cause female infertility characterized by oocyte maturation arrest

B Chen, Z Zhang, X Sun, Y Kuang, X Mao… - The American Journal of …, 2017 - cell.com
Oocyte maturation arrest results in female infertility, but the genetic determinants of human
oocyte maturation arrest remain largely unknown. Previously, we identified TUBB8 …

The human cumulus–oocyte complex gene-expression profile

S Assou, T Anahory, V Pantesco… - Human …, 2006 - academic.oup.com
BACKGROUND: The understanding of the mechanisms regulating human oocyte maturation
is still rudimentary. We have identified transcripts differentially expressed between immature …

Novel mutations and structural deletions in TUBB8: expanding mutational and phenotypic spectrum of patients with arrest in oocyte maturation, fertilization or early …

B Chen, B Li, D Li, Z Yan, X Mao, Y Xu, J Mu… - Human …, 2017 - academic.oup.com
STUDY QUESTION Are there any new type of mutations and novel phenotypes in patients
with arrest in oocyte maturation, fertilization or early embryonic development having tubulin …

Mutation analysis of the TUBB8 gene in nine infertile women with oocyte maturation arrest

L Huang, X Tong, L Luo, S Zheng, R Jin, Y Fu… - Reproductive …, 2017 - Elsevier
Mutations in the tubulin beta 8 class VIII (TUBB8) gene have been proven to cause oocyte
maturation arrest. The aim of this study was to describe newly discovered mutations in …

Dormancy and activation of human oocytes from primordial and primary follicles: molecular clues to oocyte regulation

EH Ernst, ML Grøndahl, S Grund, K Hardy… - Human …, 2017 - academic.oup.com
STUDY QUESTION Do specific transcriptome dynamics in human oocytes from primordial
and primary follicles identify novel pathways in oocyte activation? SUMMARY ANSWER The …