[HTML][HTML] Serum miRNA signature in rheumatoid arthritis and “at-risk individuals”

CC Cunningham, S Wade, A Floudas, C Orr… - Frontiers in …, 2021 - frontiersin.org
Background MicroRNAs (miRNAs) are small non-coding RNAs which have been implicated
as potential biomarkers or therapeutic targets in autoimmune diseases. This study examines …

Serum MicroRNA signature as a diagnostic and therapeutic marker in patients with psoriatic arthritis

SM Wade, T McGarry, SC Wade, U Fearon… - The Journal of …, 2020 - jrheum.org
Objective MicroRNA (miRNA) are small endogenous regulatory RNA molecules that have
emerged as potential therapeutic targets and biomarkers in autoimmunity. Here, we …

[HTML][HTML] miRNAs as biomarkers and possible therapeutic strategies in rheumatoid arthritis

T Kmiołek, A Paradowska-Gorycka - Cells, 2022 - mdpi.com
Within the past years, more and more attention has been devoted to the epigenetic
dysregulation that provides an additional window for understanding the possible …

Altered expression of microRNAs may predict therapeutic response in rheumatoid arthritis patients

M Rezaeepoor, M Pourjafar… - International …, 2020 - Elsevier
Background Epigenetic alternations of microRNAs (miRNAs) can contribute to the
pathogenesis and progression of rheumatoid arthritis (RA). This study aimed to measure the …

MiR-5571-3p and miR-135b-5p, derived from analyses of microRNA profile sequencing, correlate with increased disease risk and activity of rheumatoid arthritis

C Liu, A Pan, X Chen, J Tu, X Xia, L Sun - Clinical Rheumatology, 2019 - Springer
Objectives This study aimed to investigate microRNA (miRNA) expression profiles in
synovium tissues of rheumatoid arthritis (RA) patients by RNA sequencing and to evaluate …

Rheumatoid arthritis and miRNAs: a critical review through a functional view

MC Moran-Moguel, S Petarra-del Rio… - Journal of …, 2018 - Wiley Online Library
Rheumatoid arthritis (RA) is a systemic autoimmune disease with severe joint inflammation
and destruction associated with an inflammatory environment. The etiology behind RA …

Identification of putative miRNA biomarkers in early rheumatoid arthritis by genome-wide microarray profiling: a pilot study

MF Romo-García, Y Bastian, M Zapata-Zuñiga… - Gene, 2019 - Elsevier
Despite the existing research, the etiology of rheumatoid arthritis (RA), an autoimmune
disease remains poorly understood with early and accurate diagnosis difficult to achieve …

MicroRNAs as biomarkers in rheumatic diseases

I Alevizos, GG Illei - Nature Reviews Rheumatology, 2010 - nature.com
MicroRNAs (miRNAs) are endogenous, noncoding, single-stranded RNAs of 19–25
nucleotides in length. They regulate gene expression and are important in a wide range of …

MicroRNAs in rheumatoid arthritis: altered expression and diagnostic potential

AV Churov, EK Oleinik, M Knip - Autoimmunity reviews, 2015 - Elsevier
Rheumatoid arthritis (RA) is a polygenic disease characterized by autoimmunity and
systemic inflammation with progressive impairment of joints that results in lifelong disability …

MicroRNAs in rheumatoid arthritis: From pathogenesis to clinical impact

G Evangelatos, GE Fragoulis, V Koulouri… - Autoimmunity reviews, 2019 - Elsevier
Over the last decade, many epigenetic mechanisms that contribute in the pathogenesis of
autoimmune disorders have been revealed. MicroRNAs (miRNAs) are small, non-coding …