In this volume, an international team of experts in chronic myeloid leukemia share their
expertise. In particular, they contribute their insights on the latest advances in understanding …

Chronic myeloid leukemia (CML) is a pluripotent hematopoietic stem cell disorder leading to
myeloproliferation and its attendant consequences. In the United States, it is estimated that …

Chronic myelogenous leukemia (CML) involves the clonal expansion of hemopoietic
progenitor cells associated with a characteristic translocation between chromosomes 9 and …

Chronic myelogenous leukemia (CML) originates in a pluripotent hematopoetic stem cell of
the bone marrow and is characterized by greatly increased numbers of granulocytes in the …

Chronic myeloid leukemia (CML) is a clonal bone marrow (BM) disease characterized by
neoplastic overproduction of, mainly, granulocytes. The treatment of CML has changed …

Few neoplastic diseases have undergone a transformation in a relatively short period like
chronic myeloid leukemia (CML) has in the last few years. In 1960, CML was the first cancer …

▪ Abstract Our understanding and treatment of chronic myelogenous leukemia (CML) has
progressed since 1960 in parallel with work on cancer in general. CML provided the first …

An extraordinary series of discoveries about chronic myeloid leukemia (CML) has made this
disease a model of the way in which bench and bedside research can unite and culminate …

Chronic myeloid leukemia (CML) has been the first human malignancy to be associated,
more than 50 years ago, with a consistent chromosomal abnormality—the t (9; 22)(q34; q11) …

Chronic myelogenous leukemia (CML) is a malignant disease of the human hematopoietic
stem cell. The disease is characterized by an abnormal expansion of granulocytic …