The cortical evoked potential corresponds with deep brain stimulation efficacy in rats

IR Cassar, WM Grill - Journal of Neurophysiology, 2022 - journals.physiology.org
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) antidromically activates the
motor cortex (M1), and this cortical activation appears to play a role in the treatment of …

Stability and effect of parkinsonian state on deep brain stimulation cortical evoked potentials

BA Campbell, H Cho, RM Faulhammer… - … : Technology at the …, 2022 - Elsevier
Objectives To characterize and compare the stability of cortical potentials evoked by deep
brain stimulation (DBS) of the subthalamic nucleus (STN) across the naïve, parkinsonian …

Subthalamic stimulation evoked cortical responses relate to motor performance in Parkinson's disease

BH Bahners, RK Spooner, CJ Hartmann… - … Clinical Research in …, 2023 - brainstimjrnl.com
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an established therapy for
Parkinson's disease (PD)[1]. However, determining the optimal stimulation setting can be a …

Non-stationary discharge patterns in motor cortex under subthalamic nucleus deep brain stimulation

S Santaniello, EB Montgomery Jr, JT Gale… - Frontiers in integrative …, 2012 - frontiersin.org
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) directly modulates the basal
ganglia (BG), but how such stimulation impacts the cortex upstream is largely unknown …

Model-based deconstruction of cortical evoked potentials generated by subthalamic nucleus deep brain stimulation

K Kumaravelu, CS Oza… - Journal of …, 2018 - journals.physiology.org
Parkinson's disease is associated with altered neural activity in the motor cortex. Chronic
high-frequency deep brain stimulation (DBS) of the subthalamic nucleus (STN) is effective in …

Classification of electrically-evoked potentials in the parkinsonian subthalamic nucleus region

J Rosing, A Doyle, AM Brinda, M Blumenfeld, E Lecy… - Scientific reports, 2023 - nature.com
Electrically evoked compound action potentials (ECAPs) generated in the subthalamic
nucleus (STN) contain features that may be useful for titrating deep brain stimulation (DBS) …

[HTML][HTML] Evoked potentials reveal neural circuits engaged by human deep brain stimulation

SL Schmidt, DT Brocker, BD Swan, DA Turner, WM Grill - Brain stimulation, 2020 - Elsevier
Background Deep brain stimulation (DBS) is an effective therapy for reducing the motor
symptoms of Parkinson's disease, but the mechanisms of action of DBS and neural …

Multiple stimulation parameters influence efficacy of deep brain stimulation in parkinsonian mice

JS Schor, AB Nelson - The Journal of clinical investigation, 2019 - Am Soc Clin Investig
Deep brain stimulation (DBS) is used to treat multiple neuropsychiatric disorders, including
Parkinson's disease (PD). Despite widespread clinical use, its therapeutic mechanisms are …

Endogenous signals during active movement predict deep brain stimulation evoked potential pathways: Results of a transfer function analysis

M Kasiri, JW Hillman, E Hernandez-Martin… - medRxiv, 2023 - medrxiv.org
Deep brain stimulation (DBS) is used for targeted neuro-modulation in the treatment of
patients with movement disorders. It is often assumed that the primary effect of DBS occurs …

Direct activation of primary motor cortex during subthalamic but not pallidal deep brain stimulation

LA Johnson, J Wang, SD Nebeck, J Zhang… - Journal of …, 2020 - Soc Neuroscience
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) and globus pallidus internus
(GPi) is an effective treatment for parkinsonian motor signs. Though its therapeutic …