Helicobacter pylori infection and the cytokine-mediated inflammatory responses play
important roles in gastric cancer pathogenesis. This case control study was conducted to …

Previous studies on the association between interleukin‐1 (IL‐1) genetic polymorphisms
and the risk of gastric cancer have produced conflicting results. The purpose of this study …

Abstract Background and Aim: Helicobacter pylori is a major cause of chronic gastritis and
peptic ulcer disease and a definite carcinogen for gastric adenocarcinoma. However, the …

The incidence of gastric cancer (GC) in China is among the highest in the world. In present
work, 154 patients with GC and 166 healthy controls in population of north-western China …

Aim: Our aim was to study the relationship between interleukin 1B (IL-1B) polymorphism,
Helicobacter pylori infection, and gastric cancer in high prevalent (Shanxi) and low prevalent …

Pro-inflammatory cytokines are produced in the gastric mucosa by inflammatory cells
activated by chronic Helicobacter pylori (H. pylori) infection. Polymorphisms of these …

Studies suggest that IL-1β (encoded by IL-1B gene) is a pro-inflammatory cytokine and
potent inhibitor of gastric acid secretion, which is proposed as a key determinant in gastric …

Abstract Interleukin 2 (IL2) is a typical Th1 cytokine, and interleukin 4 (IL4) is an inducible
Th2 cytokine. These cytokines are critical mediators of the Th1/Th2 balance and apoptosis …

Background Polymorphisms in the gene for interleukin 1β (IL-1B) have been found to
increase the risks of gastric cancer and its precursors in response to Helicobacter pylori …

Background: Polymorphisms of interleukin-1B (IL1B) and its receptor antagonist (IL1RN)
genes have been inconsistently associated with gastric cancer risk. We examined these …