Bioenergetic and mitochondrial dysfunction are common hallmarks of neurodegenerative
diseases. Decades of research describe how genetic and environmental factors initiate …

Neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease,
Huntington's disease, and amyotrophic lateral sclerosis are a heterogeneous group of …

Mitochondria are multifaceted organelles that serve to power critical neuronal functions.
Additionally, mitochondria buffer calcium, produce intracellular reactive oxygen species …

Mitochondria play a multidimensional role in the function and the vitality of the neurological
system. From the generation of neural stem cells to the maintenance of neurons and their …

Mitochondria are bilayer sub-cellular organelles that are an integral part of normal cellular
physiology. They are responsible for producing the majority of a cell's ATP, thus supplying …

Neurodegenerative diseases are a heterogeneous group of disorders that are incurable and
characterized by the progressive degeneration of the function and structure of the central …

Mitochondria are involved in ATP supply to cells through oxidative phosphorylation
(OXPHOS), synthesis of key molecules and response to oxidative stress, as well as in …

Mitochondria are dynamic cellular organelles that consistently migrate, fuse, and divide to
modulate their number, size, and shape. In addition, they produce ATP, reactive oxygen …

Mitochondria play a central role in a plethora of processes related to the maintenance of
cellular homeostasis and genomic integrity. They contribute to preserving the optimal …

Mitochondria are associated with various cellular activities critical to homeostasis,
particularly in the nervous system. The plastic architecture of the mitochondrial network and …