Parallel down-regulation of FOXO1, PPARγ and adiponectin mRNA expression in visceral adipose tissue of class III obese individuals

TO Hammes, CS Costa, F Rohden, R Margis… - Obesity Facts, 2012 - karger.com
Objective: Adipose tissue is responsible for secretion of several cytokines that mediate
systemic effects on obesity and insulin resistance. Subcutaneous abdominal adipose tissue …

[HTML][HTML] Chitosan oligosaccharide activates brown adipose tissue by modulating the gut microbiota and bile acid pathways based on faecal microbiota transplantation

W Lun, J Zhou, Y Bai, Q Che, H Cao, J Guo… - Journal of Functional …, 2023 - Elsevier
Objective To study the effect of chitosan oligosaccharide with a molecular weight≤ 3000 Da
(COSM) on the energy metabolism of obese mice after faecal bacteria transplantation …

[HTML][HTML] Study on the interventional effects of Polygonatum cyrtonema polysaccharides on high-fat-diet-induced obese model mice through serum and liver …

J Liang, W Chen, K Zong, R Xu, Y Liu, N Yu… - Journal of Functional …, 2022 - Elsevier
Polygonatum cyrtonema has been traditionally used as medicine and food in China for
centuries, Polygonatum cyrtonema polysaccharides (PCP) is a principal constituent of P …

Differential proteomics of omental and subcutaneous adipose tissue reflects their unalike biochemical and metabolic properties

R Pérez-Pérez, FJ Ortega-Delgado… - Journal of proteome …, 2009 - ACS Publications
Obesity is increasing exponentially in developed countries and constitutes a public health
problem by enhancing the risk for metabolic disorder and cardiovascular disease …

Adiponectin gene therapy ameliorates high-fat, high-sucrose diet-induced metabolic perturbations in mice

AD Kandasamy, MM Sung, JJ Boisvenue, AJ Barr… - Nutrition & …, 2012 - nature.com
Methods and Results: The objective of the present study was to investigate whether gene
therapy designed to elevate circulating adiponectin levels is a viable strategy for …

Comparative effects and mechanisms of chitosan and its derivatives on hypercholesterolemia in high-fat diet-fed rats

CY Chiu, TE Yen, SH Liu, MT Chiang - International journal of molecular …, 2019 - mdpi.com
The present study investigated and compared the effects of different molecular weights of
chitosan (high molecular weight chitosan (HC) and low molecular weight chitosan (LC)) and …

Adipose tissue deficiency and chronic inflammation in diabetic Goto-Kakizaki rats

B Xue, S Sukumaran, J Nie, WJ Jusko, DC DuBois… - PLoS one, 2011 - journals.plos.org
Type 2 diabetes (T2DM) is a heterogeneous group of diseases that is progressive and
involves multiple tissues. Goto-Kakizaki (GK) rats are a polygenic model with elevated blood …

Chitosan oligosaccharides improve the disturbance in glucose metabolism and reverse the dysbiosis of gut microbiota in diabetic mice

J Zheng, X Yuan, G Cheng, S Jiao, C Feng, X Zhao… - Carbohydrate …, 2018 - Elsevier
The aim of this study is to investigate the effect of chitosan oligosaccharides (COS) on type 2
diabetes mellitus. Wild type C57BL/6J mice or diabetic db/db mice were treated with vehicle …

Functional and structural features of adipokine family

R Raucci, F Rusolo, A Sharma, G Colonna, G Castello… - Cytokine, 2013 - Elsevier
In the mid-1990s, the interest in adipose tissue was revived by the discovery of leptin. Since
then numerous other hormones have been isolated from white adipose tissue that has no …

Effect of fungal polysaccharides on the modulation of plasma proteins in streptozotocin‐induced diabetic rats

SW Kim, HJ Hwang, HM Kim, MC Lee, M Shik Lee… - …, 2006 - Wiley Online Library
To search out novel biomarkers for monitoring diabetes prognosis, we examined the effect of
hypoglycemic fungal exopolysaccharides (EPS) on the differential levels of plasma proteins …