Neisseria gonorrhoeae (N. gonorrhoeae) outer membrane protein reduction modifiable
protein (Rmp) has strong immunogenicity. However, anti-Rmp antibodies block rather than …

The continued emergence of Neisseria gonorrhoeae strains that express resistance to
multiple antibiotics, including the last drug for empiric monotherapy (ceftriaxone) …

Uncomplicated gonorrhea is most commonly an acute urogenital infection involving the
urethra in men and the endocervix in women of reproductive age. Upon entering the …

ABSTRACT The MtrC-MtrD-MtrE multidrug efflux pump of Neisseria gonorrhoeae confers
resistance to a diverse array of antimicrobial agents by transporting these toxic compounds …

Neisseria gonorrhoeae utilizes the mtrCDE-encoded efflux pump system to resist not only
host-derived, hydrophobic antimicrobials that bathe mucosal surfaces, which likely aids in its …

Iron is an essential nutrient that is sequestered by iron-binding proteins in the human host
resulting in a hostile environment for microbes. Neisseria gonorrhoeae, however, can utilize …

Neisseria gonorrhoeae is a bacterial pathogen responsible for the sexually transmitted
infection gonorrhea. Emergence of antimicrobial resistance (AMR) of N. gonorrhoeae …

Neisseria gonorrhoeae is able to utilize iron (Fe) from a variety of sources including
transferrin (TF) and lactoferrin (LF). To gain insight into the molecular mechanisms used by …

In the last several years, bacterial gene regulation via small RNAs (sRNAs) has been
recognized as an important mechanism controlling expression of essential proteins that are …

Background Neisseria gonorrhoeae can survive during oxygen starvation by reducing nitrite
to nitrous oxide catalysed by the nitrite and nitric oxide reductases, AniA and NorB. The …