Transcriptional and translational responsiveness of the Neisseria gonorrhoeae type IV secretion system to conditions of host infections

MM Callaghan, AK Klimowicz, AC Shockey… - Infection and …, 2021 - Am Soc Microbiol
The type IV secretion system of Neisseria gonorrhoeae translocates single-stranded DNA
into the extracellular space, facilitating horizontal gene transfer and initiating biofilm …

[HTML][HTML] Genetic variation regulates the activation and specificity of Restriction-Modification systems in Neisseria gonorrhoeae

L Sánchez-Busó, D Golparian, J Parkhill, M Unemo… - Scientific Reports, 2019 - nature.com
Restriction-Modification systems (RMS) are one of the main mechanisms of defence against
foreign DNA invasion and can have an important role in the regulation of gene expression …

[HTML][HTML] Comparative analysis of two Neisseria gonorrhoeae genome sequences reveals evidence of mobilization of Correia Repeat Enclosed Elements and their …

LAS Snyder, JA Cole, MJ Pallen - BMC genomics, 2009 - Springer
Abstract Background The Correia Repeat Enclosed Element (CREE) of the Neisseria spp.,
with its inverted repeat and conserved core structure, can generate a promoter sequence at …

[HTML][HTML] Mechanisms of host manipulation by Neisseria gonorrhoeae

E Walker, S van Niekerk, K Hanning, W Kelton… - Frontiers in …, 2023 - frontiersin.org
Neisseria gonorrhoeae (also known as gonococcus) has been causing gonorrhoea in
humans since ancient Egyptian times. Today, global gonorrhoea infections are rising at an …

[HTML][HTML] Dual species transcriptomics reveals conserved metabolic and immunologic processes in interactions between human neutrophils and Neisseria …

AD Potter, VL Edwards, A D'Mello, MC Gray… - PLoS …, 2024 - journals.plos.org
Neisseria gonorrhoeae (the gonococcus, Gc) causes the sexually transmitted infection
gonorrhea. Gc is a prominent threat to human health by causing severe lifelong sequelae …

Constitutively Opa-expressing and Opa-deficient Neisseria gonorrhoeae strains differentially stimulate and survive exposure to human neutrophils

LM Ball, AK Criss - Journal of bacteriology, 2013 - Am Soc Microbiol
The Neisseria gonorrhoeae (the gonococcus [Gc]) opacity-associated (Opa) proteins
mediate bacterial binding and internalization by human epithelial cells and neutrophils …

Cloning, complementation, and characterization of an rfaE homolog from Neisseria gonorrhoeae

JC Levin, DC Stein - Journal of bacteriology, 1996 - Am Soc Microbiol
Neisseria gonorrhoeae WS1 is a spontaneous pyocin (a bacteriocin produced by
Pseudomonas aeruginosa)-resistant mutant of N. gonorrhoeae FA19 that produces a …

Identification of transcription activators that regulate gonococcal adaptation from aerobic to anaerobic or oxygen‐limited growth

S Lissenden, S Mohan, T Overton… - Molecular …, 2000 - Wiley Online Library
Analysis of the Neisseria gonorrhoeae DNA sequence database revealed the presence of
two genes, one encoding a protein predicted to be 37.5% identical (50% similar) in amino …

cis- and trans-Acting Factors Influence Expression of the norM-Encoded Efflux Pump of Neisseria gonorrhoeae and Levels of Gonococcal Susceptibility to Substrate …

CE Rouquette-Loughlin, V Dhulipala… - Antimicrobial Agents …, 2018 - Am Soc Microbiol
The gonococcal NorM efflux pump exports substrates with a cationic moiety, including
quaternary ammonium compounds such as berberine (BE) and ethidium bromide (EB) as …

[HTML][HTML] RNA markers enable phenotypic test of antibiotic susceptibility in Neisseria gonorrhoeae after 10 minutes of ciprofloxacin exposure

T Khazaei, JT Barlow, NG Schoepp, RF Ismagilov - Scientific reports, 2018 - nature.com
Antimicrobial-resistant Neisseria gonorrhoeae is an urgent public-health threat, with
continued worldwide incidents of infection and rising resistance to antimicrobials. Traditional …