Towards a vaccine against Plasmodium vivax malaria
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Broadly neutralizing epitopes in the Plasmodium vivax vaccine candidate Duffy Binding Protein
Plasmodium vivax Duffy Binding Protein (PvDBP) is the most promising vaccine candidate
for P. vivax malaria. The polymorphic nature of PvDBP induces strain-specific immune …
for P. vivax malaria. The polymorphic nature of PvDBP induces strain-specific immune …
Antibody responses to Plasmodium vivax Duffy binding and Erythrocyte binding proteins predict risk of infection and are associated with protection from clinical …
Background The Plasmodium vivax Duffy Binding Protein (PvDBP) is a key target of
naturally acquired immunity. However, region II of PvDBP, which contains the receptor …
naturally acquired immunity. However, region II of PvDBP, which contains the receptor …
Identification and evaluation of universal epitopes in Plasmodium vivax Duffy binding protein
Selected PvDBP-derived synthetic peptides were tested in competition assays with HLA
molecules in order to identify and evaluate their binding to a wide range of MHC class II …
molecules in order to identify and evaluate their binding to a wide range of MHC class II …
Structural basis for inhibition of Plasmodium vivax invasion by a broadly neutralizing vaccine-induced human antibody
TA Rawlinson, NM Barber, F Mohring, JS Cho… - Nature …, 2019 - nature.com
The most widespread form of malaria is caused by Plasmodium vivax. To replicate, this
parasite must invade immature red blood cells through a process requiring interaction of the …
parasite must invade immature red blood cells through a process requiring interaction of the …
Immunogenicity of a Plasmodium vivax vaccine based on the duffy binding protein formulated using adjuvants compatible for use in humans
FJ Martinez, M Guillotte-Blisnick, C Huon, P England… - Scientific Reports, 2023 - nature.com
The invasion of reticulocytes by Plasmodium vivax merozoites is dependent on the
interaction of the Plasmodium vivax Duffy Binding Protein (PvDBP) with the Duffy antigen …
interaction of the Plasmodium vivax Duffy Binding Protein (PvDBP) with the Duffy antigen …
Preclinical assessment of the receptor-binding domain of Plasmodium vivax Duffy-binding protein as a vaccine candidate in rhesus macaques
The receptor-binding domain of Plasmodium vivax Duffy-binding protein, region II (PvRII), is
an attractive candidate for a vaccine against P. vivax malaria. Here, we have studied the …
an attractive candidate for a vaccine against P. vivax malaria. Here, we have studied the …
Immunogenicity and protective efficacy of recombinant vaccine based on the receptor-binding domain of the Plasmodium vivax Duffy binding protein in Aotus monkeys
M Arevalo-Herrera, A Castellanos… - … American journal of …, 2005 - repository.ias.ac.in
Invasion of human erythrocytes by Plasmodium vivax requires interaction between Duffy
binding protein (PvDBP) and the Duffy blood group antigen. The receptor-binding domain of …
binding protein (PvDBP) and the Duffy blood group antigen. The receptor-binding domain of …
[PDF][PDF] Serologic responses to recombinant Plasmodium vivax Duffy binding protein in a Colombian village.
PA Michon, M Arevalo-Herrera, T Fraser… - The American journal …, 1998 - researchgate.net
The Plasmodium vivax Duffy binding protein (DBP) is essential during merozoite invasion
into human erythrocytes. Because of its biological importance, the DBP is also seen to have …
into human erythrocytes. Because of its biological importance, the DBP is also seen to have …
Naturally Acquired and Vaccine-Elicited Antibodies Block Erythrocyte Cytoadherence of the Plasmodium vivaxDuffy Binding Protein
Malaria merozoites require the presence of specific surface receptors on the red blood cell
for invasion. Plasmodium vivax, requires the Duffy blood group antigen as an obligate …
for invasion. Plasmodium vivax, requires the Duffy blood group antigen as an obligate …