Air pollution and cancer: biomarker studies in human populations

P Vineis, K Husgafvel-Pursiainen - Carcinogenesis, 2005 - academic.oup.com
Large cohort studies in the US and in Europe suggest that air pollution may increase lung
cancer risk. Biomarkers can be useful to understand the mechanisms and to characterize …

Linking exposure to environmental pollutants with biological effects

M Sørensen, H Autrup, P Møller, O Hertel… - … Research/Reviews in …, 2003 - Elsevier
Exposure to ambient air pollution has been associated with cancer. Ambient air contains a
complex mixture of toxics, including particulate matter (PM) and benzene. Carcinogenic …

Air pollution exposure–DNA adduct dosimetry in humans and rodents: evidence for non-linearity at high doses

J Lewtas, D Walsh, R Williams, L Dobiáš - Mutation Research/Fundamental …, 1997 - Elsevier
The impact of air pollution exposure on the level of total DNA adducts in human white blood
cells (WBCs) was evaluated in two populations in the Czech Republic and compared to the …

Air pollution, oxidative damage to DNA, and carcinogenesis

P Møller, JK Folkmann, L Forchhammer, EV Bräuner… - Cancer letters, 2008 - Elsevier
There is growing concern that air pollution exposure increases the risk of lung cancer. The
mechanism of action is related to particle-induced oxidative stress and oxidation of DNA …

Molecular epidemiology studies of carcinogenic environmental pollutants: effects of polycyclic aromatic hydrocarbons (PAHs) in environmental pollution on …

PB Farmer, R Singh, B Kaur, RJ Sram… - … Research/Reviews in …, 2003 - Elsevier
Exposure to high levels of environmental air pollution is known to be associated with an
increased carcinogenic risk. The individual contribution to this risk derived from specific …

Biomarkers of ambient air pollution and lung cancer: a systematic review

CA Demetriou, O Raaschou-Nielsen, S Loft… - Occupational and …, 2012 - oem.bmj.com
The association between ambient air pollution exposure and lung cancer risk has been
investigated in prospective studies and the results are generally consistent, indicating that …

DNA adducts and lung cancer risk: a prospective study

M Peluso, A Munnia, G Hoek, M Krzyzanowski… - Cancer research, 2005 - AACR
Objectives were to investigate prospectively the ability of DNA adducts to predict cancer and
to study the determinants of adducts, especially air pollutants. DNA adducts were measured …

Challenges and future direction of molecular research in air pollution-related lung cancers

MS Shahadin, NSA Mutalib, MT Latif, CM Greene… - Lung Cancer, 2018 - Elsevier
Hazardous air pollutants or chemical release into the environment by a variety of natural
and/or anthropogenic activities may give adverse effects to human health. Air pollutants …

Biomarkers of genotoxicity of air pollution (the AULIS project): bulky DNA adducts in subjects with moderate to low exposures to airborne polycyclic aromatic …

P Georgiadis, J Topinka, M Stoikidou, S Kaila… - …, 2001 - academic.oup.com
The levels of bulky DNA adducts were measured by 32 P-post-labelling in lymphocytes of
194 non-smoking students living in the city of Athens and the region of Halkida, Greece …

Airborne particulate matter induces oxidative damage, DNA adduct formation and alterations in DNA repair pathways

EM Quezada-Maldonado, Y Sánchez-Pérez… - Environmental …, 2021 - Elsevier
Air pollution, which includes particulate matter (PM), is classified in group 1 as a carcinogen
to humans by the International Agency for Research in Cancer. Specifically, PM exposure …