Polycyclic aromatic hydrocarbons (PAHs), nitro-PAHs and related environmental compounds: biological markers of exposure and effects.

G Talaska, P Underwood, A Maier… - Environmental …, 1996 - ehp.niehs.nih.gov
Lung cancer caused by polycyclic aromatic hydrocarbons (PAHs), nitro-PAHs and related
environmental agents is a major problem in industrialized nations. The high case-fatality rate …

Genotoxicity biomarkers associated with exposure to traffic and near-road atmospheres: a review

DM DeMarini - Mutagenesis, 2013 - academic.oup.com
Diesel and gasoline emissions, which are the primary components of traffic exhaust, are
known or possible human carcinogens, respectively, and working or living near high-traffic …

Epigenomic alterations and gene expression profiles in respiratory epithelia exposed to cigarette smoke condensate

F Liu, JK Killian, M Yang, RL Walker, JA Hong… - Oncogene, 2010 - nature.com
Limited information is available regarding epigenomic events mediating initiation and
progression of tobacco-induced lung cancers. In this study, we established an in vitro system …

Lung cancer epigenetics and genetics

A Risch, C Plass - International journal of cancer, 2008 - Wiley Online Library
Lung cancer is the leading cause of cancer‐related death and thus a major health problem.
The efficiency of current treatment modalities for lung cancer depends strongly on the time of …

Molecular epidemiology of lung cancer

PG Shields - Annals of oncology, 1999 - Elsevier
Lung cancer occurs through a complex multistage process that results from the combination
of carcinogen exposure and genetic susceptibilities. The primary etiology of lung cancer is …

Association of outdoor air pollution, lifestyle, genetic factors with the risk of lung cancer: A prospective cohort study

H Liang, X Zhou, Y Zhu, D Li, D Jing, X Su, P Pan… - Environmental …, 2023 - Elsevier
Objectives The effect of air pollution exposure on incident lung cancer remains uncertain,
and the modifying role of lifestyle and genetic susceptibility in association between air …

[PDF][PDF] Epidemiology of lung cancer

AJ Alberg, MV Brock, JG Ford, JM Samet, SD Spivack - Chest, 2013 - aamr.org.ar
Background: Ever since a lung cancer epidemic emerged in the mid-1900s, the
epidemiology of lung cancer has been intensively investigated to characterize its causes …

Air pollution and lung cancer incidence in 17 European cohorts: prospective analyses from the European Study of Cohorts for Air Pollution Effects (ESCAPE)

O Raaschou-Nielsen, ZJ Andersen, R Beelen… - The lancet …, 2013 - thelancet.com
Background Ambient air pollution is suspected to cause lung cancer. We aimed to assess
the association between long-term exposure to ambient air pollution and lung cancer …

Ambient air pollution and cancer mortality in the cancer prevention study II

MC Turner, D Krewski, WR Diver… - Environmental …, 2017 - ehp.niehs.nih.gov
Background: The International Agency for Research on Cancer classified both outdoor air
pollution and airborne particulate matter as carcinogenic to humans (Group 1) for lung …

Is there a genetic basis for lung cancer susceptibility?

CI Amos, W Xu, MR Spitz - Chemoprevention of Cancer: A Clinical Update, 1999 - Springer
The major risk factor for lung cancer is exposure to tobacco smoke. Exposure to radon,
heavy metals used in smelting, and asbestos also greatly increase risks for lung cancer …