[HTML][HTML] Expression pattern of tumour-associated antigens in hepatocellular carcinoma: association with immune infiltration and disease progression

J Liang, T Ding, ZW Guo, XJ Yu, YZ Hu, L Zheng… - British journal of …, 2013 - nature.com
Background: The distinct expression pattern of tumour-associated antigens (TAAs) might be
a critical reason for the inefficacy of immunity-based treatments and heterogeneous …

[HTML][HTML] Comprehensive characterization of immunological profiles and clinical significance in hepatocellular carcinoma

P Tao, L Hong, W Tang, Q Lu, Y Zhao, S Zhang… - Frontiers in …, 2021 - frontiersin.org
Background Therapies targeting immune molecules have rapidly been adopted and
advanced the treatment of hepatocellular carcinoma (HCC). Nonetheless, no studies have …

[HTML][HTML] Distinct tumour antigen-specific T-cell immune response profiles at different hepatocellular carcinoma stages

C Zang, Y Zhao, L Qin, G Liu, J Sun, K Li, Y Zhao… - BMC cancer, 2021 - Springer
Abstract Background Cancer-testis antigens (CTAs) and tumour-associated antigens (TAAs)
are frequently expressed in hepatocellular carcinoma (HCC); however, the role of tumour …

Strong CD8+ T-cell responses against tumor-associated antigens prolong the recurrence-free interval after tumor treatment in patients with hepatocellular carcinoma

K Hiroishi, J Eguchi, T Baba, T Shimazaki… - Journal of …, 2010 - Springer
Aim We investigated whether tumor-specific CD8+ T-cell responses affect tumor-free
survival as well as the relationship between CD8+ T-cell responses against tumor …

[HTML][HTML] Autoantibodies to tumor-associated antigens as biomarkers in human hepatocellular carcinoma (HCC)

L Dai, N Lei, M Liu, JY Zhang - Experimental Hematology & Oncology, 2013 - Springer
Tumor-associated antigens (TAAs) recognized by cellular and/or humoral effectors of the
immune system are attractive targets for diagnostic and therapeutic approaches to human …

A classification based on tumor budding and immune score for patients with hepatocellular carcinoma

L Wei, Z Delin, Y Kefei, W Hong, H Jiwei… - …, 2020 - Taylor & Francis
Background: The role of immune profiling and tumor budding in hepatocellular carcinoma
(HCC) remains largely unknown. This study evaluated the association between tumor …

[HTML][HTML] Identification of a prognostic and therapeutic immune signature associated with hepatocellular carcinoma

Y Peng, C Liu, M Li, W Li, M Zhang, X Jiang… - Cancer cell …, 2021 - Springer
Background Hepatocellular carcinoma (HCC) is one of the most prevalent and inflammation-
associated cancers. The tumor microenvironment (TME) plays an essential role in HCC …

[HTML][HTML] An analysis of immunoreactive signatures in early stage hepatocellular carcinoma

Y Hong, J Long, H Li, S Chen, Q Liu, B Zhang, X He… - …, 2015 - thelancet.com
Background Hepatocellular carcinoma (HCC) is prevalent worldwide and early diagnosis of
HCC is critical for effective treatment and optimal prognosis. Methods Serum was screened …

[HTML][HTML] Immune signature-based hepatocellular carcinoma subtypes may provide novel insights into therapy and prognosis predictions

Q Zheng, Q Yang, J Zhou, X Gu, H Zhou, X Dong… - Cancer cell …, 2021 - Springer
Background Hepatocellular carcinoma (HCC) has a poor prognosis and has become the
sixth most common malignancy worldwide due to its high incidence. Advanced approaches …

Targeting Tumor‐Associated Antigens in Hepatocellular Carcinoma for Immunotherapy: Past Pitfalls and Future Strategies

L Lu, J Jiang, M Zhan, H Zhang, QT Wang, SN Sun… - …, 2021 - Wiley Online Library
Hepatocellular carcinoma (HCC) is a deadly cancer with a 5-year survival of 18% for
patients at all stages.(1) Systemic treatments for advanced-stage HCC, including targeted …