Simple Summary Prostate cancer is still the most common cancer among men in the US.
Current standard-of-care therapies for metastatic castration-resistant prostate cancer can …

Prostate cancer (PCa) is the second leading cause of cancer related death in men in the
United States, suggesting that novel molecular targets as well as the development of agents …

Cancer stem cells (CSCs), or tumor-initiating cells, are involved in tumor progression and
metastasis. MicroRNAs (miRNAs) regulate both normal stem cells and CSCs,,,, and …

The Reproducibility Project: Cancer Biology seeks to address growing concerns about
reproducibility in scientific research by conducting replications of selected experiments from …

Prostate cancer (PrCa) is the most common type of cancer among men in the United States.
The metastatic and advanced PrCa develops drug resistance to current regimens which …

As part of the Reproducibility Project: Cancer Biology, we published a Registered Report (Li
et al., 2015), that described how we intended to replicate selected experiments from the …

MicroRNA-34a (miR-34a) is a tumor suppressor that has attracted considerable attention in
recent years. It modulates cancer cell invasion, metastasis, and drug resistance, and has …

Background: The microRNA, miR-34c, is a well-established regulator of tumour suppression.
It is downregulated in most forms of cancers and inhibits malignant growth by repressing …

Prostate cancer (PCa) is the most frequent and age-related cancer in men: about 20% of the
worldwide male population will develop this kind of tumor during their lifetime and 2–3% will …

The importance of miRNAs in the progression of prostate cancer (PCa) has further been
supported by the finding that miRNAs have been identified as potential oncogenes or tumor …