We investigated the association between esophageal cancer and cachexia–anorexia
syndrome (CAS) of the alimentary tract and leptin, an adipocytokine crucial for body weight …

Obesity is a well‐established risk factor for the development and mortality from several
cancers, including adenocarcinoma of the oesophagus, oesophago‐gastric junction and …

Recent studies have suggested that circulating concentrations of leptin might play a role in
cancer cachexia. In the first part of the study, we compared circulating concentrations of free …

Leptin is a recently identified hormone produced by the adipocyte ob gene which acts as a
negative feedback signal critical to the normal control of food intake and body weight. A …

Obesity has been associated with many types of cancer, including colorectal cancer (CRC).
The mechanisms by which obesity increases the risk for development of CRC can be …

Background Serum leptin level is associated with appetite and energy expenditure in
healthy individuals. We aimed to evaluate the serum leptin concentration and the other …

Leptin, a peptide hormone produced primarily by the adipocytes, is hypothesized to play a
role in the pathogenesis of colorectal cancer (CRC). Soluble leptin receptor (sOB-R) may …

Obesity is an important risk factor for esophageal adenocarcinoma (EAC), and elevated
serum leptin is characteristic of obesity. We hypothesized that leptin may have biological …

Leptin may support the proliferation and hinder the apoptosis of tumor cells. Although leptin
expression has been studied in several human tumors, its potential clinical significance …

Background: Obesity is associated with increased risks of Barrett's oesophagus and
oesophageal adenocarcinoma. Alterations in serum leptin and adiponectin, obesity-related …