Cancer is one of the leading causes of death worldwide, despite the large efforts to improve
the understanding of cancer biology and development of treatments. The attempts to …

Three-dimensional cancer-on-a-chip tissue models aim to replicate the key hallmarks of the
tumour microenvironment and allow for the study of dynamic interactions that occur during …

In vitro tumor models have played vital roles in enhancing the understanding of the cellular
and molecular composition of tumors, as well as their biochemical and biophysical …

Cancer kills millions of individuals every year all over the world (Global Cancer
Observatory). The physiological and biomechanical processes underlying the tumor are still …

One of the hurdles to the development of new anticancer therapies is the lack of in vitro
models which faithfully reproduce the in vivo tumor microenvironment (TME). Understanding …

Over the past six decades the inflation-adjusted cost to bring a new drug to market has been
increasing constantly and doubles every 9 years–now reaching in excess of $2.5 billion …

Tumors are a major cause of death worldwide, and much effort has been made to develop
appropriate anti-tumor therapies. Existing in vitro and in vivo tumor models cannot reflect the …

Microfluidic tumors‐on‐chips models have revolutionized anticancer therapeutic research
by creating an ideal microenvironment for cancer cells. The tumor microenvironment (TME) …

Every year, cancer claims millions of lives around the globe. Unfortunately, model systems
that accurately mimic human oncology–a requirement for the development of more effective …

Cancer is one of the leading causes of human death, despite enormous efforts to explore
cancer biology and develop anticancer therapies. The main challenges in cancer research …