Effective immunochemotherapy for aggressive non-Hodgkin's lymphoma

B Coiffier - Seminars in oncology, 2004 - Elsevier
In the past, CHOP chemotherapy (cyclophosphamide, doxorubicin, vincristine, prednisone)
was considered the gold standard treatment for aggressive non-Hodgkin's lymphoma (NHL) …

Immunochemotherapy: the new standard in aggressive non-Hodgkin's lymphoma in the elderly

B Coiffier - Seminars in oncology, 2003 - Elsevier
Rituximab is an anti-CD20 chimeric monoclonal antibody that has shown substantial activity
in indolent non-Hodgkin's lymphoma (NHL). Recent data indicate that the clinical benefits …

Recent developments in the treatment of aggressive non-Hodgkin lymphoma

AS Michallet, B Coiffier - Blood reviews, 2009 - Elsevier
Options for treating aggressive non-Hodgkin lymphoma (NHL) have expanded in recent
years. In phase 3 clinical trials, giving rituximab with cyclophosphamide, vincristine …

Improving second-line therapy in aggressive non-Hodgkin's lymphoma

C Gisselbrecht, N Mounier - Seminars in oncology, 2004 - Elsevier
The prognosis is poor for patients relapsing following treatment with standard chemotherapy
for aggressive non-Hodgkin's lymphoma. High-dose therapy and autologous stem cell …

Treatment of aggressive non-Hodgkin's lymphoma: a north American perspective.

LH Sehn, JM Connors - Oncology (Williston Park, NY), 2005 - europepmc.org
The most common subtype of aggressive non-Hodgkin's lymphoma is diffuse large B-cell
lymphoma (DLBCL). Diffuse large B-cell lymphoma represents a heterogeneous entity, with …

Best treatment of aggressive non-Hodgkin's lymphoma: a French perspective.

B Coiffier, F Reyes - Oncology (Williston Park, NY), 2005 - europepmc.org
The Groupe d'Etude des Lymphomes de l'Adulte (GELA) has conducted several phase II
and III studies in patients with aggressive lymphoma, diffuse large B-cell lymphoma …

Rituximab in combination with CHOP improves survival in elderly patients with aggressive non-Hodgkin's lymphoma

B Coiffier - Seminars in oncology, 2002 - Elsevier
Diffuse large B-cell lymphoma (DLCL) is the most frequently diagnosed subtype of non-
Hodgkin's lymphoma (NHL), and more than 50% of cases present in patients over 60 years …

New treatment strategies for aggressive lymphoma

A Younes - Seminars in oncology, 2004 - Elsevier
For the past three decades chemotherapy with CHOP (cyclophosphamide/doxorubicin/
vincristine/prednisone) has been the standard treatment for aggressive non-Hodgkin's …

Long-term update of a phase II study of rituximab in combination with CHOP chemotherapy in patients with previously untreated, aggressive non-Hodgkin's lymphoma

JM Vose, BK Link, ML Grossbard… - Leukemia & …, 2005 - Taylor & Francis
The present study aimed to determine the long-term safety and efficacy of chimeric anti-CD
20 antibody rituxan (rituximab, Biogen IDEC, San Diego, CA, USA; Genentech, South San …

Intensified CHOP with Rituximab for Intermediate or High-Risk Non-Hodgkin's Lymphoma: Interim Analysis of a Randomized Phase III Trial in Elderly Patients by the …

P Sonneveld, W van Putten, H Holte, D Biesma… - 2005 - ashpublications.org
Abstract High-risk Non-Hodgkin lymphoma (NHL) in elderly patients (> 60 yrs) is associated
with a relatively low complete response (CR) rate and a poor overall survival (OS). Previous …