[HTML][HTML] Application potential of toll-like receptors in cancer immunotherapy: Systematic review

M Shi, X Chen, K Ye, Y Yao, Y Li - Medicine, 2016 - journals.lww.com
Abstract Toll-like receptors (TLRs), as the most important pattern recognition receptors in
innate immunity, play a pivotal role in inducing immune response through recognition of …

[HTML][HTML] The critical role of Toll-like receptor-mediated signaling in cancer immunotherapy

X Chen, Y Zhang, Y Fu - Medicine in Drug Discovery, 2022 - Elsevier
Toll-like receptors (TLR) play a dual regulatory role in the tumor microenvironment (TME).
TLR agonists (TLRa) elicit both innate and adaptive immune responses to achieve anti …

[PDF][PDF] Targeting Toll-like receptors against cancer

B Du, QL Jiang, J Cleveland… - Journal of Cancer …, 2016 - pdfs.semanticscholar.org
The discovery of Toll-like receptors (TLRs) about 20 years ago was a remarkable
achievement not only in the field of immunology but also in the field of medicine. The TLRs …

[HTML][HTML] The role of toll-like receptor in inflammation and tumor immunity

X Cen, S Liu, K Cheng - Frontiers in pharmacology, 2018 - frontiersin.org
Toll-like receptors (TLRs) activation enables host to recognize a large number of pathogen-
associated molecule patterns (PAMPs), ignite immune cells to discriminate between self and …

[HTML][HTML] Immunotherapeutic implications of toll-like receptors activation in tumor microenvironment

R Zheng, J Ma - Pharmaceutics, 2022 - mdpi.com
Toll-like receptors (TLRs) play an important role between innate and adaptive immunity as
one of the pattern recognition receptors (PRRs). Both immune cells and tumor cells express …

Targeting toll-like receptors for cancer therapy

MJ Braunstein, J Kucharczyk, S Adams - Targeted oncology, 2018 - Springer
The immune system encompasses a broad array of defense mechanisms against foreign
threats, including invading pathogens and transformed neoplastic cells. Toll-like receptors …

[HTML][HTML] Toll-like receptors from the perspective of cancer treatment

N Javaid, S Choi - Cancers, 2020 - mdpi.com
Toll-like receptors (TLRs) represent a family of pattern recognition receptors that recognize
certain pathogen-associated molecular patterns and damage-associated molecular …

Roles of toll-like receptors in cancer: a double-edged sword for defense and offense

S Basith, B Manavalan, TH Yoo, SG Kim… - Archives of pharmacal …, 2012 - Springer
Toll-like receptors (TLRs) belong to a class of pattern-recognition receptors that play an
important role in host defense against pathogens by recognizing a wide variety of pathogen …

Toll-like receptors: cost or benefit for cancer?

T Matijevic, J Pavelic - Current pharmaceutical design, 2010 - ingentaconnect.com
The function of the Toll-like receptor (TLR) family members has been extensively studied in
the recent decades. The TLR family is generally involved in the defense against microbial …

Trial Watch: Toll-like receptor agonists in cancer immunotherapy

M Smith, E García-Martínez, MR Pitter… - …, 2018 - Taylor & Francis
Toll-like receptor (TLR) agonists demonstrate therapeutic promise as immunological
adjuvants for anticancer immunotherapy. To date, three TLR agonists have been approved …