Meiosis is the specialized cell division during which parental genomes recombine to create
genotypically unique gametes. Despite its importance, mammalian meiosis cannot be …

Meiosis is a conserved cell division process that is used by sexually reproducing organisms
to generate haploid gametes. Males and females produce different end products of meiosis …

Sexual reproduction depends on the success of faithful chromosome transmission during
meiosis to yield viable gametes. Central to meiosis is the process of recombination between …

During meiosis, chromosomes exhibit dramatic changes in morphology and intranuclear
positioning. How these changes influence homolog pairing, alignment, and recombination …

Meiosis is a highly conserved and essential process in gametogenesis in sexually
reproducing organisms. However, there are substantial sex-specific differences within …

Meiosis facilitates diversity across individuals and serves as a major driver of evolution.
However, understanding how meiosis begins is complicated by fundamental differences that …

Background Meiotic recombination hotspots control the frequency and distribution of Spo11
(Rec12)-initiated recombination in the genome. Recombination occurs within and is …

Meiosis is a specialized type of cell division that creates haploid germ cells and ensures
their genetic diversity through homologous recombination. We show that the H3K4me3 …

Molecular studies of meiosis in mammals have been long relegated due to some intrinsic
obstacles, namely the impossibility to reproduce the process in vitro, and the difficulty to …

Male spermatogenesis is an essential and complex process necessary to gain totipotency
and allow a whole new organism to develop upon fertilization. While single-gene based …