YAP1 is involved in tumorigenic properties of prostate cancer cells
Abstract The Yes Associated Protein 1 (YAP1) is a transcriptional cofactor negatively
regulated by Hippo Pathway. The dysregulation of the pathway has been shown to have a …
regulated by Hippo Pathway. The dysregulation of the pathway has been shown to have a …
[HTML][HTML] Increased expression of YAP1 in prostate cancer correlates with extraprostatic extension
Objective: Yes associated protein 1 (YAP1) is a member of the Hippo pathway, acting as a
transcriptional coactivator. To elucidate the role of YAP1 and phosphorylated (p) YAP1 in …
transcriptional coactivator. To elucidate the role of YAP1 and phosphorylated (p) YAP1 in …
[HTML][HTML] Yes-associated protein expression is correlated to the differentiation of prostate adenocarcinoma
Background Yes-associated protein (YAP) in the Hippo signaling pathway is a growth
control pathway that regulates cell proliferation and stem cell functions. Abnormal regulation …
control pathway that regulates cell proliferation and stem cell functions. Abnormal regulation …
The hippo pathway effector YAP regulates motility, invasion, and castration-resistant growth of prostate cancer cells
Yes-associated protein (YAP) is an effector of the Hippo tumor suppressor pathway. The
functional significance of YAP in prostate cancer has remained elusive. In this study, we first …
functional significance of YAP in prostate cancer has remained elusive. In this study, we first …
YAP is closely correlated with castration-resistant prostate cancer, and downregulation of YAP reduces proliferation and induces apoptosis of PC-3 cells
X Sheng, WB Li, DL Wang… - Molecular …, 2015 - spandidos-publications.com
Yes-associated protein 65 (YAP65) has been implicated as an oncogene, and its expression
is increased in human cancer. Previous studies have demonstrated that alterations in YAP …
is increased in human cancer. Previous studies have demonstrated that alterations in YAP …
Down-regulation of Yes Associated Protein 1 expression reduces cell proliferation and clonogenicity of pancreatic cancer cells
CH Diep, KM Zucker, G Hostetter, A Watanabe, C Hu… - PloS one, 2012 - journals.plos.org
Background The Hippo pathway regulates organ size by inhibiting cell proliferation and
promoting cell apoptosis upon its activation. The Yes Associated Protein 1 (YAP1) is a …
promoting cell apoptosis upon its activation. The Yes Associated Protein 1 (YAP1) is a …
[HTML][HTML] YAP knockdown inhibits proliferation and induces apoptosis of human prostate cancer DU145 cells
X Jin, W Zhao, P Zhou, T Niu - Molecular medicine …, 2018 - spandidos-publications.com
The role of yes-associated protein (YAP) in human prostate cancer DU145 cells and its
underlying molecular mechanisms were explored in the present study. Initially, the …
underlying molecular mechanisms were explored in the present study. Initially, the …
YES-associated protein 1 promotes adenocarcinoma growth and metastasis through activation of the receptor tyrosine kinase Axl
ZL Cui, FF Han, XH Peng, X Chen… - International journal …, 2012 - journals.sagepub.com
Yes-associated protein 1 (YAP1), a nuclear effector of the Hippo pathway, plays an
important role in tumorigenesis and progression of multiple cancers. The present study …
important role in tumorigenesis and progression of multiple cancers. The present study …
Loss of YAP protein in prostate cancer is associated with Gleason score increase
X Hu, Y Jia, J Yu, J Chen, Q Fu - Tumori Journal, 2015 - journals.sagepub.com
Aims and Background To investigate the expression of YAP protein by
immunohistochemistry in prostate cancer tissues and hyperplasia or normal prostate tissues …
immunohistochemistry in prostate cancer tissues and hyperplasia or normal prostate tissues …
The dual functions of YAP-1 to promote and inhibit cell growth in human malignancy
H Wang, YC Du, X Zhou, H Liu, SC Tang - Cancer and Metastasis Reviews, 2014 - Springer
The major functions of Hippo (Hpo) signaling pathway are to control cell growth,
proliferation, and apoptosis. As its important downstream player, yes-associated protein …
proliferation, and apoptosis. As its important downstream player, yes-associated protein …