Recently, many G-protein-coupled receptors (GPCRs) have been demonstrated to form
constitutive dimers consisting of identical or distinct monomeric subunits. The discovery of …

Although classical models predict that G-protein-coupled receptors (GPCRs) function as
monomers, several recent studies acknowledge that GPCRs exist as dimeric or oligomeric …

G protein-coupled receptors (GPCRs) are cell surface receptors that mediate physiological
responses to a diverse array of stimuli. GPCRs have traditionally been thought to act as …

The classical idea that G‐protein‐coupled receptors (GPCRs) function as monomeric
entities has been unsettled by the emerging concept of GPCR dimerization. Recent findings …

G-protein-coupled receptors (GPCRs) comprise the largest family of transmembrane
receptors in the human genome that respond to a plethora of signals, including …

Although highly controversial just a few years ago, the idea that G‐protein‐coupled
receptors (GPCRs) may undergo homo‐oligomerization or hetero‐oligomerization has …

With an ever-expanding need for reliable therapeutic agents that are highly effective and
exhibit minimal deleterious side effects, a greater understanding of the mechanisms …

G protein coupled receptors (GPCRs) are one of the largest human gene families, and are
targets for many important therapeutic drugs. Over the last few years, there has been a major …

A wide range of techniques have been employed to examine the quaternary structure of G-
protein-coupled receptors (GPCRs). Although it is well established that homo-dimerisation is …

G protein-coupled receptors (GPCRs) can exist as dimers or as larger oligomeric clusters
that enable intercommunication between different receptor protomers within the same …