[HTML][HTML] Development of a compartmental model for studying vitamin A kinetics and status in theoretical lactating women

V Lopez-Teros, MH Green, J Avila-Prado… - The Journal of …, 2022 - Elsevier
Background Low vitamin A status and suboptimal milk vitamin A concentrations are
problems in many populations worldwide. However, limited research has been done on …

[HTML][HTML] Use of compartmental modeling and datasets for theoretical lactating women to determine conditions under which vitamin A–specific activity in breast milk …

MH Green, V Lopez-Teros, J Avila-Prado… - The Journal of …, 2022 - Elsevier
Background Vitamin A concentrations in breast milk are related to maternal vitamin A intake
and status. Objectives Our objective was to identify conditions under which vitamin A specific …

[HTML][HTML] Direct Use of Plasma or Milk Vitamin A Specific Activity Data to Model Retinol Kinetics and Predict Vitamin A Stores in Theoretical Lactating Women

MH Green, V Lopez-Teros, J Avila-Prado… - The Journal of nutrition, 2022 - Elsevier
Background Many applications of the Simulation, Analysis and Modeling software use data
on the fraction of an orally administered tracer dose (FD) in plasma; thus, researchers must …

[HTML][HTML] Compartmental modeling of vitamin A stable isotope data from milk or plasma provides comparable predictions of vitamin A stores in theoretical lactating …

MH Green, V Lopez-Teros, J Avila-Prado… - The Journal of nutrition, 2022 - Elsevier
Background Previous compartmental models describing and quantifying whole-body vitamin
A (VA) metabolism have been developed from plasma retinol kinetic data after human …

[HTML][HTML] Incremental Improvements in Vitamin A Model-Based Compartmental Analysis in Anticipation of Real Data in Lactating Women

SA Tanumihardjo - The Journal of nutrition, 2022 - Elsevier
Major strides have been made globally to eradicate blindness due to vitamin A (VA)
deficiency, but VA status assessments are still important for monitoring intervention …

[HTML][HTML] Duration of retinol isotope dilution studies with compartmental modeling affects model complexity, kinetic parameters, and calculated vitamin A stores in US …

BM Gannon, AR Valentine, CR Davis, JA Howe… - The Journal of …, 2018 - Elsevier
Background Retinol isotope dilution (RID) indirectly estimates vitamin A (VA) status.
Multicompartment modeling of RID data is used to refine study designs and equations to …

Use of Theoretical Women and Model-Based Compartmental Analysis to Evaluate the Impact of Vitamin A Intake With or Without a Daily Vitamin A Supplement on …

MH Green, V Lopez-Teros, J Avila-Prado… - The Journal of …, 2024 - Elsevier
Abstract Background Inadequate vitamin A (VA) intake is common among lactating women
in many communities worldwide, but high dose VA supplementation of postpartum women is …

[HTML][HTML] Breast milk retinol concentrations reflect total liver vitamin A reserves and dietary exposure in Thai lactating women from urban and rural areas

K Nimmannun, CR Davis, P Srisakda, BM Gannon… - The Journal of …, 2022 - Elsevier
ABSTRACT Background Measuring vitamin A (VA) status during lactation is required to
inform dietary recommendations. Limited data exist on VA stores in women. Objectives Our …

[HTML][HTML] Addition of vitamin A intake data during compartmental modeling of retinol kinetics in theoretical humans leads to accurate prediction of vitamin A total body …

JL Ford, JB Green, MH Green - The Journal of Nutrition, 2019 - Elsevier
Background Mathematical modeling of theoretical data has been used to validate
experimental protocols and methods in several fields. Objective We hypothesized that …

[HTML][HTML] Use of model-based compartmental analysis and theoretical data to further explore choice of sampling time for assessing vitamin A status in groups and …

MH Green, JB Green - The Journal of Nutrition, 2021 - Elsevier
Background An optimal blood sampling time for application of the retinol isotope dilution
(RID) method for predicting vitamin A total body stores (TBS)(ie, vitamin A status) has not …