Clinical pharmacokinetics of oral semaglutide: analyses of data from clinical pharmacology trials
RV Overgaard, A Navarria, SH Ingwersen… - Clinical …, 2021 - Springer
Objective The absorption, distribution and elimination of oral semaglutide, the first oral
glucagon-like peptide-1 receptor agonist for treating type 2 diabetes, was investigated using …
glucagon-like peptide-1 receptor agonist for treating type 2 diabetes, was investigated using …
Semaglutide sc once-weekly in type 2 diabetes: a population pharmacokinetic analysis
KC Carlsson Petri, SH Ingwersen, A Flint, J Zacho… - Diabetes Therapy, 2018 - Springer
Introduction Semaglutide, a new treatment option approved for the treatment of patients with
type 2 diabetes mellitus, is a glucagon-like peptide-1 receptor agonist to be injected …
type 2 diabetes mellitus, is a glucagon-like peptide-1 receptor agonist to be injected …
Effect of various dosing conditions on the pharmacokinetics of oral semaglutide, a human glucagon-like peptide-1 analogue in a tablet formulation
TA Bækdal, A Breitschaft, M Donsmark, SJ Maarbjerg… - Diabetes Therapy, 2021 - Springer
Introduction Oral semaglutide is a novel tablet formulation of the human glucagon-like
peptide-1 analogue semaglutide. In two trials, the effects of prior food ingestion (food effect) …
peptide-1 analogue semaglutide. In two trials, the effects of prior food ingestion (food effect) …
Pharmacokinetics, safety and tolerability of oral semaglutide in subjects with renal impairment
C Granhall, FL Søndergaard, M Thomsen… - Clinical …, 2018 - Springer
Background Semaglutide, a glucagon-like peptide-1 (GLP-1) analogue, has been co-
formulated with the absorption enhancer sodium N-(8-[2-hydroxybenzoyl] amino) caprylate …
formulated with the absorption enhancer sodium N-(8-[2-hydroxybenzoyl] amino) caprylate …
Pharmacokinetics and tolerability of a single dose of semaglutide, a human glucagon-like peptide-1 analog, in subjects with and without renal impairment
TC Marbury, A Flint, JB Jacobsen… - Clinical …, 2017 - Springer
Background The pharmacokinetics and tolerability of semaglutide, a once-weekly human
glucagon-like peptide-1 analog in development for the treatment of type 2 diabetes mellitus …
glucagon-like peptide-1 analog in development for the treatment of type 2 diabetes mellitus …
Safety and pharmacokinetics of single and multiple ascending doses of the novel oral human GLP-1 analogue, oral semaglutide, in healthy subjects and subjects with …
C Granhall, M Donsmark, TM Blicher, G Golor… - Clinical …, 2019 - Springer
Background Oral semaglutide is a novel tablet containing the human glucagon-like peptide-
1 (GLP‑1) analogue semaglutide, co-formulated with the absorption enhancer sodium N-(8 …
1 (GLP‑1) analogue semaglutide, co-formulated with the absorption enhancer sodium N-(8 …
Management of type 2 diabetes with oral semaglutide: Practical guidance for pharmacists
MP Kane, CL Triplitt… - American Journal of …, 2021 - academic.oup.com
Purpose To provide pharmacists with information on counseling patients with type 2
diabetes (T2D) receiving oral semaglutide. Summary Oral semaglutide, the first oral …
diabetes (T2D) receiving oral semaglutide. Summary Oral semaglutide, the first oral …
Real-World Use of Oral Semaglutide in Adults with Type 2 Diabetes in the PIONEER REAL Netherlands Multicentre, Prospective, Observational Study
W van Houtum, P Schrömbges, H Amadid… - Diabetes Therapy, 2024 - Springer
Introduction In this phase 4, multicentre, prospective, non-interventional PIONEER REAL
Netherlands study, we assessed clinical outcomes associated with once-daily oral …
Netherlands study, we assessed clinical outcomes associated with once-daily oral …
Efficacy and safety of once-daily oral semaglutide 25 mg and 50 mg compared with 14 mg in adults with type 2 diabetes (PIONEER PLUS): a multicentre, randomised …
VR Aroda, J Aberle, L Bardtrum, E Christiansen… - The Lancet, 2023 - thelancet.com
Background Once-daily oral semaglutide is an effective type 2 diabetes treatment. We aimed
to investigate a new formulation of oral semaglutide at higher investigational doses versus …
to investigate a new formulation of oral semaglutide at higher investigational doses versus …
Effect of semaglutide on the pharmacokinetics of metformin, warfarin, atorvastatin and digoxin in healthy subjects
H Hausner, J Derving Karsbøl, AG Holst… - Clinical …, 2017 - Springer
Abstract Background and Objective Semaglutide is a glucagon-like peptide-1 analogue in
development for the once-weekly treatment of type 2 diabetes mellitus. Its effect on the rate …
development for the once-weekly treatment of type 2 diabetes mellitus. Its effect on the rate …
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