Coagulation and sepsis

M Levi, T van der Poll - Thrombosis research, 2017 - Elsevier
Severe sepsis is almost invariably associated with systemic activation of coagulation. There
is ample evidence that demonstrates a wide-ranging cross-talk between hemostasis and …

Coagulation in patients with severe sepsis

M Levi, T van der Poll - Seminars in thrombosis and …, 2015 - thieme-connect.com
In the majority of patients with severe sepsis, systemic activation of coagulation is present.
Increasing evidence points to an extensive cross-talk between coagulation and inflammation …

The coagulant response in sepsis and inflammation

M Levi - Hämostaseologie, 2010 - thieme-connect.com
Critically ill patients often have systemic activation of both inflammation and coagulation.
Increasing evidence points to an extensive cross-talk between these two systems, whereby …

Inflammation and coagulation

M Levi - … : From Molecular and Cellular Mechanisms to the Clinic, 2017 - Wiley Online Library
In the majority of patients with systemic inflammatory conditions, some degree of activation
of coagulation is present. Increasing evidence points to an extensive cross‐talk between …

The role of natural anticoagulants in the pathogenesis and management of systemic activation of coagulation and inflammation in critically ill patients

M Levi, T van der Poll - Seminars in thrombosis and …, 2008 - thieme-connect.com
Critically ill patients often have systemic activation of both inflammatory systems and
coagulation. Increasing evidence points to an extensive cross-talk between these two …

Coagulation in sepsis

A Amaral, SM Opal, JL Vincent - Intensive care medicine, 2004 - Springer
Coagulation abnormalities, ranging from a simple fall in platelet count to full-blown
disseminated intravascular coagulation, are a common occurrence in critically ill patients …

Systemic versus localized coagulation activation contributing to organ failure in critically ill patients

M Levi, T van der Poll, M Schultz - Seminars in immunopathology, 2012 - Springer
In the pathogenesis of sepsis, inflammation and coagulation play a pivotal role. Increasing
evidence points to an extensive cross-talk between these two systems, whereby …

Sepsis and thrombosis

M Levi, M Schultz, T van der Poll - Seminars in thrombosis and …, 2013 - thieme-connect.com
Activation of coagulation frequently occurs in severe infection and sepsis and may contribute
to the development of thrombosis. Coagulation abnormalities in sepsis range from a small …

Coagulation in severe sepsis: a central role for thrombomodulin and activated protein C

SN Faust, RS Heyderman, M Levin - Critical care medicine, 2001 - journals.lww.com
Coagulation in severe sepsis: A central role for thrombomodu... : Critical Care Medicine
Coagulation in severe sepsis: A central role for thrombomodulin and activated protein C …

Coagulopathy of acute sepsis

N Semeraro, CT Ammollo, F Semeraro… - … in thrombosis and …, 2015 - thieme-connect.com
Coagulopathy is common in acute sepsis and may range from subclinical activation of blood
coagulation (hypercoagulability), which may contribute to venous thromboembolism, to …