Do incretins improve endothelial function?
J Oyama, Y Higashi, K Node - Cardiovascular diabetology, 2014 - Springer
An impaired endothelial function has been recognized in the early stage of atherosclerosis,
and is a major factor affecting the future development of cardiovascular events. Type 2 …
and is a major factor affecting the future development of cardiovascular events. Type 2 …
The safety of incretin-based therapies—review of the scientific evidence
DJ Drucker, SI Sherman… - The Journal of Clinical …, 2011 - academic.oup.com
Context: Antidiabetic therapies based on potentiation of incretin action are now widely used;
however, understanding of their long-term safety remains incomplete. Evidence Acquisition …
however, understanding of their long-term safety remains incomplete. Evidence Acquisition …
The role of glucagon‐like peptide‐1 impairment in obesity and potential therapeutic implications
S Madsbad - Diabetes, Obesity and Metabolism, 2014 - Wiley Online Library
The hormone glucagon‐like peptide‐1 (GLP‐1) is released from the gut in response to food
intake. It acts as a satiety signal, leading to reduced food intake, and also as a regulator of …
intake. It acts as a satiety signal, leading to reduced food intake, and also as a regulator of …
GLP-1 receptor agonists and cardiovascular disease: a meta-analysis of recent cardiac outcome trials
Purpose The aim of this study is to examine the cardioprotective properties of Glucagon-like
peptide-1 receptor agonist, a class of antihyperglycemic therapy, via meta-analysis of four …
peptide-1 receptor agonist, a class of antihyperglycemic therapy, via meta-analysis of four …
[HTML][HTML] GLP-1 receptor agonists and reduction of cardiometabolic risk: Potential underlying mechanisms
Type 2 diabetes mellitus (T2DM) is a metabolic condition with an elevated impact on
cardiovascular (CV) risk. The innovative therapeutic approaches for T2DM-incretin-based …
cardiovascular (CV) risk. The innovative therapeutic approaches for T2DM-incretin-based …
The incretin hormones: from scientific discovery to practical therapeutics
S Mudaliar, RR Henry - Diabetologia, 2012 - Springer
The incretins are gut hormones secreted in response to nutrient/carbohydrate ingestion and
act on the pancreatic beta cell to amplify glucose-stimulated insulin secretion. Incretin …
act on the pancreatic beta cell to amplify glucose-stimulated insulin secretion. Incretin …
Clarifying the role of incretin-based therapies in the treatment of type 2 diabetes mellitus
RK Campbell - Clinical therapeutics, 2011 - Elsevier
Background Glucose homeostasis is the result of a complex interaction of a spectrum of
hormones, including insulin, glucagon, amylin, and the incretins. Incretins are released by …
hormones, including insulin, glucagon, amylin, and the incretins. Incretins are released by …
Incretin hormones in obesity and related cardiometabolic disorders: the clinical perspective
J Michałowska, E Miller-Kasprzak, P Bogdański - Nutrients, 2021 - mdpi.com
The prevalence of obesity continues to grow rapidly worldwide, posing many public health
challenges of the 21st century. Obese subjects are at major risk for serious diet-related …
challenges of the 21st century. Obese subjects are at major risk for serious diet-related …
Update on incretin hormones
LK Phillips, JB Prins - Annals of the New York Academy of …, 2011 - Wiley Online Library
The incretin hormones glucagon‐like‐peptide‐1 (GLP‐1) and glucose‐dependent
insulinotropic polypeptide (GIP) are released from the intestine following oral ingestion of …
insulinotropic polypeptide (GIP) are released from the intestine following oral ingestion of …
Gip as a potential therapeutic target for atherosclerotic cardiovascular disease–a systematic review
Y Mori, T Matsui, T Hirano, S Yamagishi - International Journal of …, 2020 - mdpi.com
Glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1)
are gut hormones that are secreted from enteroendocrine L cells and K cells in response to …
are gut hormones that are secreted from enteroendocrine L cells and K cells in response to …