Background: A substantial portion of stroke risk remains unexplained, and a contribution
from genetic factors is supported by recent findings. In most cases, genetic risk factors …

The etiology of ischemic stroke is multifactorial. Although receiving less emphasis, genetic
causes make a significant contribution to ischemic stroke genesis, especially in early-onset …

Although stroke remains a leading cause of disability and mortality worldwide, recently there
have been significant advances related to our understanding of the genetic basis of stroke …

Epidemiologic evidence supports a genetic predisposition to stroke. Recent advances,
primarily using the genome-wide association study approach, are transforming what we …

The genetics of cerebrovascular disease is an area of increasing interest and advances.
During the past year there have been a number of significant discoveries in the area that …

Ischemic stroke is a heterogeneous condition influenced by a combination of genetic and
environmental factors. Recent advancements have explored genetics in relation to various …

The field of medical and population genetics in stroke is moving at a rapid pace and has led
to unanticipated opportunities for discovery and clinical applications. Genome-wide …

Matarin M, Singleton A, Hardy J, Meschia J (Laboratory of Neurogenetics, Bethesda, MD,
USA; UCL Institute of Neurology, London, UK; Mayo Clinic, Jacksonville, FL, USA). The …

As a result of technological advances, the genomic analysis of stroke has shifted from
candidate gene association studies to genome-wide association studies (GWAS). Agnostic …

Stroke is the second leading cause of death worldwide and a complex, heterogeneous
condition. In this review, we provide an overview of the current knowledge on monogenic …