Immune protection against infectious diseases is most effective if located at the portal of
entry of the pathogen. Hence, there is an increasing demand for vaccine formulations that …

Mucosal (and in minor extent transcutanous) stimulation can induce local or distant mucosa
secretory IgA. Liposomes and other vesicles as mucosal and transcutaneous adjuvants are …

Since the discovery of liposomes by Alec Bangham in mid-1960s, these phospholipid
vesicles have been widely used as pharmaceutical carriers. Liposomes have been …

Importance of the field: Among the particulate systems that have been envisaged in vaccine
delivery, liposomes are very attractive. These phospholipid vesicles can indeed deliver a …

Among the various particulate delivery systems, liposomes—bubble-like nano/microsized
lipidic bilayer structures—have shown great promise as an antigen-carrying vehicle. Few …

Mucosal administration of vaccines has many advantages compared to parenteral
vaccination. Needle-free mucosal vaccination would be easily applicable, target the vaccine …

Vaccination is the most effective means of preventing infectious diseases and saving lives.
Modern biotechnology largely enabled vaccine development. In the meantime, recent …

The discovery of liposomes in 1965 by Bangham and coworkers changed the prospects of
drug delivery systems. Since then, the application of liposomes as vaccine delivery systems …

The development of subunit vaccines has become very attractive in recent years due to their
superior safety profiles as compared to traditional vaccines based on live attenuated or …

Subunit vaccination benefits from improved safety over attenuated or inactivated vaccines,
but their limited capability to elicit long-lasting, concerted cellular and humoral immune …