Cerebrospinal fluid biomarkers of neurovascular dysfunction in mild dementia and Alzheimer's disease
MD Sweeney, AP Sagare… - Journal of Cerebral …, 2015 - journals.sagepub.com
Alzheimer's disease (AD) is the most common form of age-related dementias. In addition to
genetics, environment, and lifestyle, growing evidence supports vascular contributions to …
genetics, environment, and lifestyle, growing evidence supports vascular contributions to …
Vascular dysfunction in Alzheimer's disease: a prelude to the pathological process or a consequence of it?
K Govindpani, LG McNamara, NR Smith… - Journal of clinical …, 2019 - mdpi.com
Alzheimer's disease (AD) is the most prevalent form of dementia. Despite decades of
research following several theoretical and clinical lines, all existing treatments for the …
research following several theoretical and clinical lines, all existing treatments for the …
Murine beta-amyloid (1–42) oligomers disrupt endothelial barrier integrity and VEGFR signaling via activating astrocytes to release deleterious soluble factors
Transgenic mouse models of Alzheimer's disease (AD) overexpress mutations of the human
amyloid protein precursor (APP) and presenilin-1 (PSEN1) genes, which are known causes …
amyloid protein precursor (APP) and presenilin-1 (PSEN1) genes, which are known causes …
Understanding risk factors for Alzheimer's disease: interplay of neuroinflammation, connexin-based communication and oxidative stress
Alzheimer's disease (AD) is an age-related neurodegenerative disease characterized by
dementia and the presence of amyloid plaques and anomalous tau aggregates. Although …
dementia and the presence of amyloid plaques and anomalous tau aggregates. Although …
[PDF][PDF] Vascular and nonvascular mechanisms of cognitive impairment and dementia
Aging, familial gene mutations, and genetic, environmental, and modifiable lifestyle risk
factors predispose individuals to cognitive impairment or dementia by influencing the …
factors predispose individuals to cognitive impairment or dementia by influencing the …
The Vascular-immune hypothesis of Alzheimer's disease
Alzheimer's disease (AD) is a devastating and irreversible neurodegenerative disorder with
unknown etiology. While its cause is unclear, a number of theories have been proposed to …
unknown etiology. While its cause is unclear, a number of theories have been proposed to …
Systemic inflammation, blood-brain barrier vulnerability and cognitive/non-cognitive symptoms in Alzheimer disease: relevance to pathogenesis and therapy
S Takeda, N Sato, R Morishita - Frontiers in aging neuroscience, 2014 - frontiersin.org
The incidence of dementia is increasing at an alarming rate, and has become a major public
health concern. Alzheimer disease (AD) is the most common form of dementia and is …
health concern. Alzheimer disease (AD) is the most common form of dementia and is …
Common signaling pathways involved in Alzheimer's disease and stroke: Two Faces of the Same Coin
TK Das, BP Ganesh… - Journal of Alzheimer's …, 2023 - content.iospress.com
Alzheimer's disease (AD) and stroke are two interrelated neurodegenerative disorders
which are the leading cause of death and affect the neurons in the brain and central nervous …
which are the leading cause of death and affect the neurons in the brain and central nervous …
Employing new cellular therapeutic targets for Alzheimer's disease: a change for the better?
ZZ Chong, F Li, K Maiese - Current neurovascular research, 2005 - ingentaconnect.com
Alzheimer's disease is a progressive disorder that results in the loss of cognitive function
and memory. Although traditionally defined by the presence of extracellular plaques of …
and memory. Although traditionally defined by the presence of extracellular plaques of …
Contribution of cerebral microvascular mechanisms to age-related cognitive impairment and dementia
X Fang, RF Crumpler, KN Thomas… - Physiology …, 2022 - akjournals.com
Cognitive impairment and dementia are significant health burdens worldwide. Aging,
hypertension, and diabetes are the primary risk factors for Alzheimer's disease and …
hypertension, and diabetes are the primary risk factors for Alzheimer's disease and …