Plasma glucose-lowering effect of β-endorphin in streptozotocin-induced diabetic rats

JT Cheng, IM Liu, TF Tzeng, CC Tsai… - … and metabolic research, 2002 - thieme-connect.com
The effect of β-endorphin on plasma glucose levels was investigated in streptozotocin-
induced diabetic rats (STZ-diabetic rats). A dose-dependent lowering of plasma glucose was …

Infusion of β-endorphin improves insulin resistance in fructose-fed rats

CF Su, YY Chang, HH Pai, IM Liu… - Hormone and …, 2004 - thieme-connect.com
In an attempt to probe the effect of β-endorphin on insulin resistance, we used Wistar rats
that were fed fructose-rich chow to induce insulin resistance. Insulin action on glucose …

Mediation of β-endorphin by isoferulic acid to lower plasma glucose in streptozotocin-induced diabetic rats

IM Liu, WC Chen, JT Cheng - Journal of Pharmacology and Experimental …, 2003 - ASPET
We investigated the mechanism (s) by which isoferulic acid lowers plasma glucose levels in
streptozotocin-induced diabetic rats (STZ-diabetic rats). In STZ-diabetic rats, isoferulic acid …

β-Endorphin–Induced Inhibition and Stimulation of Insulin Secretion in Normal Humans Is Glucose Dependent

D Giugliano, D Cozzolino, T Salvatore, R Torella… - Diabetes, 1988 - Am Diabetes Assoc
This study evaluated the effect of human β-endorphin on pancreatic hormone levels and
their responses to nutrient challenges in normal subjects. Infusion of 0.5 mg/h β-endorphin …

Increase of β-endorphin biosynthesis in the adrenal gland of streptozotocin-induced diabetic rats

CT Hsu, IM Liu, JT Cheng - Neuroscience letters, 2002 - Elsevier
Opioid plays an important role in the regulation of glucose homeostasis in diabetic rats
lacking insulin. The present study investigated the changes of β-endorphin biosynthesis in …

Dual action of beta-endorphin on insulin release in genetically obese and lean mice

XZ Khawaja, IC Green - Peptides, 1991 - Elsevier
Intraperitoneal administration of beta-endorphin (1 mg/kg) to ob/ob mice doubled fasting
plasma insulin concentrations within 30 min, while plasma glucose concentrations were …

Regulation of insulin and glucose plasma levels by central nervous system β-endorphin in preweanling rats

JV BARTOLOME, MB BARTOLOME, EB HARRIS… - …, 1989 - academic.oup.com
Recently, our laboratory has reported that central administration of β-endorphin to rat pups
decreases hepatic and renal ornithine decarboxylase activity, a sensitive biochemical index …

In vivo and in vitro effects of β-endorphin on glucose metabolism in the rat

M Matsumura, T Fukushima, H Saito… - … and metabolic research, 1984 - thieme-connect.com
The effects of β-endorphin (β-Ep) on plasma glucose levels in rats and on glucose
metabolism in isolated rat liver cells were examined. Intravenous injection of β-Ep (5 μg/100 …

Streptozocin diabetes alters immunoreactive β-endorphin levels and pain perception after 8 wk in female rats

LJ Forman, S Estilow, M Lewis, P Vasilenko - Diabetes, 1986 - Am Diabetes Assoc
Plasma, pituitary, and hypothalamic levels of the endogenous opioid peptide β-endorphin
were measured by radioimmunoassay and column chromatography in female rats 8 wk after …

Release of β-endorphin by caffeic acid to lower plasma glucose in streptozotocin-induced diabetic rats

JT Cheng, IM Liu, TF Tzeng, WC Chen… - Hormone and …, 2003 - thieme-connect.com
The role of α 1A-adrenoceptors in the regulation of opioid secretion from the adrenal glands
of streptozotocin-induced diabetic rats (STZ-diabetic rats) was examined in an attempt to …