Background: Leptin is an adipocyte-derived neurohormone, high levels of which are found
in obese individuals. Leptin controls energy expenditure, acting in the brain, and regulates …

Leptin, the product of the ob gene, is an adipocyte-derived neurohormone that regulates
body fat storage and feeding behavior. Some studies have suggested that leptin has growth …

Background: The leptin receptor is involved in modulating leptin activity, acting as a carrier
protein. A link between leptin or leptin receptor and cancer development has been proposed …

Background & Aims: Obesity increases the risk of colon cancer, whereas physical activity
reduces the risk. Plasma levels of leptin increase in proportion to the level of obesity and are …

AIM: To examine the expression of leptin and its receptor, OB-R, in normal gastric mucosa
and neoplasia. METHODS: By immunohistochemical staining using specific antibodies, we …

Background The obesity hormone, leptin, has been found to play a role in development and
proliferation of normal and malignant tissues. Leptin activity is mediated through the leptin …

Aims and Background Leptin is a protein that affects the metabolic, neuroendocrine,
reproductive and hematopoietic systems and is involved in the regulation of body weight …

Although a number of recent studies have reported the involvement of leptin in colorectal
carcinogenesis, findings are contradictory and difficult to interpret. Our group has previously …

Leptin is a hormone which controls fat metabolism. Leptin plasma levels and adipose tissue
mRNA expression were measured in cancer patients. Plasma levels were correlated with …

Background Serum leptin level is associated with appetite and energy expenditure in
healthy individuals. We aimed to evaluate the serum leptin concentration and the other …