Alcohol is a psychoactive substance that is widely used and, unfortunately, often abused. In
addition to acute effects such as intoxication, it may cause many chronic pathological …

Alcohol consumption causes damage to various organs and systems. Liver is a primary
target for the detrimental effects of alcohol since this substance of abuse is mainly …

Alcohol dependence is a major disease burden of adults in modern society worldwide.
There is no cure for alcohol dependence. In this study, we have examined the molecular …

Substance use disorder is an emerging problem concerning to human health, causing
severe side effects, including neurotoxicity. The use of illegal drugs and the misuse of …

In the early decades of the 20 th century, discussions regarding alcohol were dominantly
directed toward its therapeutic uses, but authorities now state that any level of alcohol …

Biochemical studies on the central nervous system (CNS) are confounded by its extreme
heterogeneity and complexity. Billions of cells of diverse types and sizes are distributed in …

Unmanaged sudden withdrawal from the excessive consumption of alcohol (ethanol)
adversely alters neuronal integrity in vulnerable brain regions such as the cerebellum …

BACKGROUND: Alcoholism is a major psychiatric condition at least partly associated with
ethanol (EtOH)-induced cell damage. Although brain cell loss has been reported in subjects …

Chronic alcohol consumption is a world-wide socioeconomic problem. Three metabolic
pathways of ethanol were describe in human-alcohol dehydrogenase (ADH), microsomal …

This comprehensive handbook is a" one-stop-shop" for all researchers involved in the field
of alcohol-related harm at the whole body or cellular level. Over 100 chapters provide …