Current advances in drug discovery for Chagas disease
CB Scarim, DH Jornada, RC Chelucci… - European journal of …, 2018 - Elsevier
Chagas disease, also known as American trypanosomiasis, is one of the 17 neglected
tropical diseases (NTDs) according to World Health Organization. It is estimated that 8–10 …
tropical diseases (NTDs) according to World Health Organization. It is estimated that 8–10 …
[HTML][HTML] Drug discovery for chagas disease: A viewpoint
JM Kratz - Acta tropica, 2019 - Elsevier
Chagas disease is a neglected tropical disease caused by the protozoan parasite
Trypanosoma cruzi. It is a significant public health problem, affecting millions of people …
Trypanosoma cruzi. It is a significant public health problem, affecting millions of people …
Challenges in Chagas disease drug discovery: a review
R Paucar, E Moreno-Viguri… - Current Medicinal …, 2016 - ingentaconnect.com
Chagas disease or American trypanosomiasis is a neglected tropical disease caused by the
parasite Trypanosoma cruzi. Although the number of infected individuals has decreased …
parasite Trypanosoma cruzi. Although the number of infected individuals has decreased …
Challenges in Chagas disease drug development
AF Francisco, S Jayawardhana, F Olmo, MD Lewis… - Molecules, 2020 - mdpi.com
The protozoan parasite Trypanosoma cruzi causes Chagas disease, an important public
health problem throughout Latin America. Current therapeutic options are characterised by …
health problem throughout Latin America. Current therapeutic options are characterised by …
Second Generation of Mannich Base-Type Derivatives with in Vivo Activity against Trypanosoma cruzi
R Martin-Escolano, E Moreno-Viguri… - Journal of medicinal …, 2018 - ACS Publications
Chagas disease is a potentially life-threatening and neglected tropical disease caused by
Trypanosoma cruzi. One of the most important challenges related to Chagas disease is the …
Trypanosoma cruzi. One of the most important challenges related to Chagas disease is the …
[HTML][HTML] The translational challenge in Chagas disease drug development
Chagas disease is a neglected tropical disease caused by the protozoan parasite
Trypanosoma cruzi. There is an urgent need for safe, effective, and accessible new …
Trypanosoma cruzi. There is an urgent need for safe, effective, and accessible new …
Advances in preclinical approaches to Chagas disease drug discovery
F Villalta, G Rachakonda - Expert opinion on drug discovery, 2019 - Taylor & Francis
ABSTRACT Introduction: Chagas disease affects 8–10 million people worldwide, mainly in
Latin America. The current therapy for Chagas disease is limited to nifurtimox and …
Latin America. The current therapy for Chagas disease is limited to nifurtimox and …
[HTML][HTML] Screening of potential anti-Trypanosoma cruzi candidates: in vitro and in vivo studies
CS Maria de Nazaré, SL de Castro - The Open Medicinal …, 2011 - ncbi.nlm.nih.gov
Chagas disease (CD), caused by the intracellular protozoan Trypanosoma cruzi, is a
parasitic illness endemic in Latin America. In the centennial after CD discovery by Carlos …
parasitic illness endemic in Latin America. In the centennial after CD discovery by Carlos …
An insight on targets and patented drugs for chemotherapy of Chagas disease
VG Duschak, AS Couto - Recent patents on anti-infective drug …, 2007 - ingentaconnect.com
Chagas disease or American Trypanosomiasis, a parasitic infection typically spread by
triatomine bugs, affects millions of people throughout Latin America. Current chemotherapy …
triatomine bugs, affects millions of people throughout Latin America. Current chemotherapy …
Therapeutical approaches under investigation for treatment of Chagas disease
Introduction: A century after its discovery, American trypanosomiasis or Chagas disease
remains a serious health problem in Latin America, where it affects around 7–8 million …
remains a serious health problem in Latin America, where it affects around 7–8 million …