HIV-1/Treponema pallidum (T. pallidum) coinfection has become a global challenge, and
three monocyte subsets express varying levels of the chemokine receptors CCR2 and …

CD8+ T cells responding to chronic infection adapt an altered differentiation program that
provides some restraint on pathogen replication yet limits immunopathology. This adaptation …

Objective: Cysteine-cysteine receptor 5 (CCR5)-using viruses classically predominate
during HIV-1 primary infection but the frequency of cysteine-X-cysteine receptor 4 (CXCR4) …

In addition to the CD4 molecule that binds to the human immunodeficiency virus type-1 (HIV-
1) envelope glycoprotein gp120, productive HIV-1 infection requires interaction with cellular …

To better define a mechanism underlying the increase in expression of certain
proinflammatory chemokines during HIV-1 infection, we analyzed the effect of X4 HIV-1 …

Chemokines are chemoattractant cytokines involved in the immune response of a wide
variety of diseases. There are few studies assessing their role in opportunistic infections in …

The unexpected encounter between the fields of HIV and chemokines has opened new
perspectives for understanding the mechanisms of AIDS pathogenesis, as well as for the …

Abstract Background Chemokine ligand 13 (CXCL13) is believed to play a role in the
recruitment of B cells in the central nervous system during neuroinflammation. Neurosyphilis …

Chemokines were presumed to be an important mainly for inflammatory reactions. However,
subsequent studies provided definitive evidence that chemokines coordinately regulate the …

HIV infection is characterized by gradual immune system collapse and hematopoietic
dysfunction. We recently showed that HIV enters multipotent hematopoietic progenitor cells …