Distinct roles of chromosome-versus plasmid-encoded genital tract virulence factors in promoting Chlamydia muridarum colonization in the gastrointestinal tract

JJ Koprivsek, T Zhang, Q Tian, Y He, H Xu… - Infection and …, 2019 - Am Soc Microbiol
The genital pathogen Chlamydia is known to colonize the gastrointestinal tract. Orally
delivered Chlamydia muridarum can reach the colon and maintain a long-lasting …

[HTML][HTML] Intranasal Vaccination with Chlamydia pneumoniae Induces Cross-Species Immunity against Genital Chlamydia muridarum Challenge in Mice

S Manam, BKR Chaganty, SJ Evani, MT Zafiratos… - PLoS …, 2013 - journals.plos.org
Chlamydia trachomatis is the most common bacterial sexually transmitted disease in the
world and specifically in the United States, with the highest incidence in age-groups 14–19 …

Attachment of Chlamydia trachomatis L2 to host cells requires sulfation

DM Rosmarin, JE Carette, AJ Olive… - Proceedings of the …, 2012 - National Acad Sciences
Chlamydia trachomatis is a pathogen responsible for a prevalent sexually transmitted
disease. It is also the most common cause of infectious blindness in the developing world …

Transformation of Chlamydia muridarum reveals a role for Pgp5 in suppression of plasmid-dependent gene expression

Y Liu, C Chen, S Gong, S Hou, M Qi, Q Liu… - Journal of …, 2014 - Am Soc Microbiol
Transformation of Chlamydia trachomatis should greatly advance the chlamydial research.
However, significant progress has been hindered by the failure of C. trachomatis to induce …

Plasmid deficiency in urogenital isolates of Chlamydia trachomatis reduces infectivity and virulence in a mouse model

IM Sigar, JH Schripsema, Y Wang… - Pathogens and …, 2014 - academic.oup.com
We hypothesized that the plasmid of urogenital isolates of Chlamydia trachomatis would
modulate infectivity and virulence in a mouse model. To test this hypothesis, we infected …

Characterization of Pathogenic CD8+ T cells in Chlamydia-Infected OT1 Mice

Z Zhou, Q Tian, L Wang, X Sun, N Zhang… - Infection and …, 2022 - Am Soc Microbiol
Chlamydia trachomatis is a leading infectious cause of infertility in women due to its
induction of lasting pathology such as hydrosalpinx. Chlamydia muridarum induces mouse …

[HTML][HTML] Conservation of the glycogen metabolism pathway underlines a pivotal function of storage polysaccharides in Chlamydiae

M Colpaert, D Kadouche, M Ducatez, T Pillonel… - Communications …, 2021 - nature.com
The order Chlamydiales includes obligate intracellular pathogens capable of infecting
mammals, fishes and amoeba. Unlike other intracellular bacteria for which intracellular …

Identification of antigen-specific antibody responses associated with upper genital tract pathology in mice infected with Chlamydia muridarum

H Zeng, S Gong, S Hou, Q Zou, G Zhong - Infection and immunity, 2012 - Am Soc Microbiol
Urogenital infection with Chlamydia trachomatis in some women can lead to upper genital
tract pathologies, such as hydrosalpinx, potentially affecting fertility. In the current study, 27 …

Cleavage of the N-Linked Oligosaccharide from the Surfaces of Chlamydia Species Affects Infectivity in the Mouse Model of Lung Infection

LA Campbell, A Lee, C Kuo - Infection and immunity, 2006 - Am Soc Microbiol
Previous studies determined that the Chlamydia glycan contains a high-mannose
oligosaccharide, which is involved in attachment and infectivity of the organism, and that …

Orchestration of the mammalian host cell glucose transporter proteins-1 and 3 by Chlamydia contributes to intracellular growth and infectivity

X Wang, K Hybiske, RS Stephens - Pathogens and Disease, 2017 - academic.oup.com
Chlamydia are gram-negative obligate intracellular bacteria that replicate within a discrete
cellular vacuole, called an inclusion. Although it is known that Chlamydia require essential …