Inhibition of TRPM7 blocks MRTF/SRF-dependent transcriptional and tumorigenic activity
S Voringer, L Schreyer, W Nadolni, MA Meier… - Oncogene, 2020 - nature.com
Myocardin-related transcription factors A and B (MRTFs) are coactivators of Serum
Response Factor (SRF) that mediates the expression of genes involved in cell proliferation …
Response Factor (SRF) that mediates the expression of genes involved in cell proliferation …
TRPM8 inhibition regulates the proliferation, migration and ROS metabolism of bladder cancer cells
Introduction Based on accumulating evidence, transient receptor potential (TRP) ion
channels may play important roles in the occurrence and the progression of cancer. TRP …
channels may play important roles in the occurrence and the progression of cancer. TRP …
TRPM8: a potential target for cancer treatment
Z Liu, H Wu, Z Wei, X Wang, P Shen, S Wang… - Journal of cancer …, 2016 - Springer
Transient receptor potential (TRP) cation channel superfamily plays critical roles in variety of
processes, including temperature perception, pain transduction, vasorelaxation, male …
processes, including temperature perception, pain transduction, vasorelaxation, male …
TRPM2 in Cancer
BA Miller - Cell Calcium, 2019 - Elsevier
The TRP ion channel TRPM2 has an essential function in cell survival and protects the
viability of a number of cell types after oxidative stress. It is highly expressed in many …
viability of a number of cell types after oxidative stress. It is highly expressed in many …
TRPM2-AS promotes cancer cell proliferation through control of TAF15
L Pan, Y Li, L Jin, J Li, A Xu - The international journal of biochemistry & …, 2020 - Elsevier
Background Colorectal cancer (CRC) ranks the third among all common malignancy
worldwide. Long noncoding RNAs (lncRNAs) have been demonstrated as implicated in …
worldwide. Long noncoding RNAs (lncRNAs) have been demonstrated as implicated in …
[HTML][HTML] Roles of TRPM7 in ovarian cancer
ZB Wang, X Zhang, F Xiao, ZQ Liu, QJ Liao… - Biochemical …, 2023 - Elsevier
Ovarian cancer stands as the prevailing gynecologic malignancy, afflicting over 313,959
individuals annually worldwide, accompanied by more than 207,252 fatalities. Perturbations …
individuals annually worldwide, accompanied by more than 207,252 fatalities. Perturbations …
TRPM7 regulates AKT/FOXO1–dependent tumor growth and is an independent prognostic indicator in renal cell carcinoma
Z Zhao, M Zhang, X Duan, Y Chen, E Li, L Luo… - Molecular Cancer …, 2018 - AACR
Transient receptor potential melastatin 7 (TRPM7) is important for the tumorigenesis and
progression of several cancers. However, little is known about TRPM7 expression and its …
progression of several cancers. However, little is known about TRPM7 expression and its …
[PDF][PDF] TRPM2 Silencing Causes G2/M Arrest and Apoptosis in Lung Cancer Cells via Increasing Intracellular ROS and RNS Levels and Activating the JNK Pathway.
Abstract Background/Aims: The oxidative stress sensor transient receptor potential
melastatin-2 (TRPM2) ion channel has recently gained attention in many types of cancer …
melastatin-2 (TRPM2) ion channel has recently gained attention in many types of cancer …
[HTML][HTML] Decreased TRPM7 inhibits activities and induces apoptosis of bladder cancer cells via ERK1/2 pathway
R Cao, Z Meng, T Liu, G Wang, G Qian, T Cao… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Transient receptor potential melastatin 7 (TRPM7) functions as a Mg 2+/Ca 2+-permeable
channel fused with a kinase domain and regulates various physical processes and …
channel fused with a kinase domain and regulates various physical processes and …
TRPM8 facilitates proliferation and immune evasion of esophageal cancer cells
X Lan, J Zhao, C Song, Q Yuan, X Liu - Bioscience Reports, 2019 - portlandpress.com
Esophageal cancer is seen with increasing incidence, but the underlying mechanism of
esophageal cancer is still unknown. Transient receptor potential melastatin (TRPM) is non …
esophageal cancer is still unknown. Transient receptor potential melastatin (TRPM) is non …