Abstract Purpose of Review Osteosarcoma (OSA) is the most common primary tumor of
bone, mainly affecting children and adolescents. Here we discuss recent advances in …

Simple Summary Osteosarcoma is the most common malignant bone tumor in children, with
a 5-year survival rate ranging from 70% to 20% depending on the aggressiveness of the …

Osteosarcoma (OS) is the most common non-hematologic malignant tumor of bone in adults
and children. As sarcomas are more common in adolescents and young adults than most …

Osteosarcoma is the most common primary malignant tumour of the bone. Osteosarcoma
incidence is bimodal, peaking at 18 and 60 years of age, and is slightly more common in …

Osteosarcoma (OS) is a class of cancer originating from bone, mainly afflicting children or
young adults. It is the second highest cause of cancer-related death in these age groups …

Major advances have been achieved in the treatment of osteosarcoma with the discovery of
several chemotherapeutic agents that were active in the disease. These agents comprise …

Osteosarcoma is the most frequent malignant primary bone tumor and a main cause of
cancer-related death in children and adolescents. Although long-term survival in localized …

Osteosarcoma is the most common primary bone tumor in childhood and adolescence. The
use of combination chemotherapy and surgery enables long-term survival in approximately …

High-grade osteosarcomas are the most common primary malignant tumors of bone. With
complete surgical resection and multi-agent chemotherapy up to 70% of patients with high …

Osteosarcoma is the most common malignant primary bone tumor in children and
adolescents. Current optimal treatment for osteosarcoma consists of multi-agent …