Adequate energy intake is vital for the survival of humans and is regulated by complex
homeostatic and hedonic mechanisms. Supported by functional MRI (fMRI) studies that …

New Findings What is the topic of this review? This report provides an overview of how
functional neuroimaging technology has accelerated our understanding of human eating …

Obesity is a neurobehavioral disorder that results from a combination of overeating and
insufficient physical activity. Finely tuned mechanisms exist to match food intake to caloric …

Obese individuals exhibit brain functional abnormalities in multiple regions implicated in
reward/motivation, emotion/memory, homeostatic regulation, and executive control when …

Objectives Food intake in obesity has been found to be reward-based and less contingent
on homeostatic needs. Accordingly, previous studies investigating neural processing of food …

Insufficient responses to hypocaloric diets have been attributed to hormonal adaptations that
override self-control of food intake. We tested this hypothesis by measuring circulating …

Functional neuroimaging has become a widely used tool in obesity and eating disorder
research to explore the alterations in neurobiology that underlie overeating and binge eating …

Appetite and body weight regulation are controlled by the central nervous system (CNS) in a
rather complicated manner. The human brain plays a central role in integrating internal and …

Objective: To develop a non-invasive method of studying brain mechanisms involved in
energy homeostasis and appetite regulation in humans by using visual food cues that are …

BACKGROUND Obesity affects many aspects of health, including reproduction. Despite
unrelenting warnings about the health consequences of obesity, its prevalence continues to …