B-cell activation factor from the tumor necrosis factor family (BAFF) is a key survival factor
during B-cell maturation—a delicate immune checkpoint for B cells. Excessive BAFF …

The BAFF system plays a key role in the development of autoimmunity, especially in
systemic lupus erythematosus (SLE). This often leads to the assumption that BAFF is mostly …

The tumour necrosis factor (TNF) family members B cell activating factor (BAFF) and APRIL
(a proliferation-inducing ligand) are crucial survival factors for peripheral B cells. An excess …

Many rheumatic diseases have an autoimmune basis, characterized by organ-specific
inflammation and tissue destruction. Diseases such as rheumatoid arthritis, systemic lupus …

BAFF [B‐cell activating factor belonging to the tumor necrosis factor (TNF) family] is a ligand
that is required for peripheral B‐cell survival and homeostasis. In addition to mediating B …

The B cell-stimulating molecules, BAFF (B cell activating factor) and APRIL (a proliferation-
inducing ligand), are critical factors in the maintenance of the B cell pool and humoral …

BAFF (B lymphocyte activating factor of the tumour necrosis factor family) is a vital
homeostatic cytokine for B cells that helps regulate both innate and adaptive immune …

B cells play a pivotal role in autoimmunity not only by producing pathogenic autoantibodies
but also by modulating immune responses via the production of cytokines and chemokines …

BAFF and APRIL are TNF-like cytokines that support survival and differentiation of B cells.
The early appreciation that overexpression of BAFF leads to B cell expansion and a lupus …

Introduction: The B-cell activating factor (BAFF) axis comprises two ligands (BAFF and
APRIL) and three receptors (BCMA, TACI, BR3). BAFF is a vital B-cell survival factor and …