Population genetic models for polygenic variation and evolution.

M Turelli - 1988 - cabidigitallibrary.org
Equations for changes in the mean, variance and higher-order moments of a quantitative
trait are used to address the maintenance of heritable variation by mutation-selection …

Phenotypic evolution, constant covariances, and the maintenance of additive variance

M Turelli - Evolution, 1988 - JSTOR
I will argue that these problems are decoupled in prac-tice, because detailed genetic models
do not make useful predictions conceming the dynamics of the critical variance and …

Quantitative genetic variability maintained by mutation-stabilizing selection balance in finite populations

PD Keightley, WG Hill - Genetics Research, 1988 - cambridge.org
Models of variability in quantitative traits maintained by a balance between mutation and
stabilizing selection are investigated. The effects of mutant alleles are assumed to be …

The evolution of continuous variation. III. Joint transmission of genotype, phenotype and environment

LL Cavalli-Sforza, MW Feldman - Genetics, 1978 - academic.oup.com
Evolutionary models of continuous traits are developed. The models are based on the ideas
that:(1) the phenotype is the result of the interaction between genotype and environment;(2) …

Maintenance of genetic heterogeneity.

ER Dempster - 1955 - cabidigitallibrary.org
It is unlikely that mutation pressure in favour of completely recessive deleterious genes is
responsible for more than a very little additive genetic variance in fitness. If, however, the …

The evolution of continuous variation. II. complex transmission and assortative mating.

MW Feldman, LL Cavalli-Sforza - 1977 - cabidigitallibrary.org
In the 1st paper of this series [see ABA 44, 6010], a model was formulated for the evolution
of continuous variation. The present paper incorporates 2 modifications. Firstly, the …

On the distribution of the mean and variance of a quantitative trait under mutation-selection-drift balance.

R Bürger, R Lande - Genetics, 1994 - academic.oup.com
The distributions of the mean phenotype and of the genetic variance of a polygenic trait
under a balance between mutation, stabilizing selection and genetic drift are investigated …

The maintenance of polygenic variation in finite populations

D Houle - Evolution, 1989 - Wiley Online Library
Models of the maintenance of genetic variance in a polygenic trait have usually assumed
that population size is infinite and that selection is weak. Consequently, they will …

The divergence of a polygenic system subject to stabilizing selection, mutation and drift

N Barton - Genetics Research, 1989 - cambridge.org
Polygenic variation can be maintained by a balance between mutation and stabilizing
selection. When the alleles responsible for variation are rare, many classes of equilibria may …

The maintenance of polygenic variation through a balance between mutation and stabilizing selection

NH Barton - Genetics Research, 1986 - cambridge.org
The maintenance of polygenic variation through a balance between mutation and stabilizing
selection can be approximated in two ways. In the 'Gaussian'approximation, a normal …