Enabling multiplexed electrochemical detection of biomarkers with high sensitivity in complex biological samples

SS Timilsina, P Jolly, N Durr, M Yafia… - Accounts of Chemical …, 2021 - ACS Publications
Conspectus The ability to perform multiplexed detection of various biomarkers within
complex biological fluids in a robust, rapid, sensitive, and cost-effective manner could …

Antifouling strategies in advanced electrochemical sensors and biosensors

PH Lin, BR Li - Analyst, 2020 - pubs.rsc.org
Electrochemical biosensors have been applied in a broad range of clinical applications for
pathogen biomarker detection and medical applications and diagnosis due to the sensitivity …

Antifouling strategies for electrochemical biosensing: mechanisms and performance toward point of care based diagnostic applications

MJ Russo, M Han, PE Desroches, CS Manasa… - ACS …, 2021 - ACS Publications
Although there exist numerous established laboratory-based technologies for sample
diagnostics and analyte detection, many medical and forensic science applications require …

Ultrarapid method for coating electrochemical sensors with antifouling conductive nanomaterials enables highly sensitive multiplexed detection in whole blood

SS Timilsina, N Durr, M Yafia, H Sallum… - Advanced …, 2022 - Wiley Online Library
The commercialization of electrochemical (EC)‐sensors for medical diagnostics is currently
limited by their rapid fouling in biological fluids, and use of potential antifouling coatings is …

Electrochemical methods for the analysis of clinically relevant biomolecules

M Labib, EH Sargent, SO Kelley - Chemical reviews, 2016 - ACS Publications
Rapid progress in identifying biomarkers that are hallmarks of disease has increased
demand for high-performance detection technologies. Implementation of electrochemical …

Low fouling strategies for electrochemical biosensors targeting disease biomarkers

N Liu, Z Xu, A Morrin, X Luo - Analytical Methods, 2019 - pubs.rsc.org
Over the past few years, different biomarkers related to various disease states have been
identified, and the assay of these disease biomarkers, which can reveal the health status …

An antifouling coating that enables affinity-based electrochemical biosensing in complex biological fluids

J Sabaté del Río, OYF Henry, P Jolly… - Nature …, 2019 - nature.com
Affinity-based electrochemical detection in complex biological fluids could enable
multiplexed point-of-care diagnostics for home healthcare; however, commercialization of …

Anti-fouling strategies of electrochemical sensors for tumor markers

G Song, H Han, Z Ma - Sensors, 2023 - mdpi.com
The early detection and prognosis of cancers require sensitive and accurate detection
methods; with developments in medicine, electrochemical biosensors have been developed …

A sample-to-answer electrochemical biosensor system for biomarker detection

K Kikkeri, D Wu, J Voldman - Lab on a Chip, 2022 - pubs.rsc.org
Biomarker detection is critical for the diagnosis and treatment of numerous diseases.
Typically, target biomarkers in blood samples are measured through tests conducted at …

Biofabrication of multiplexed electrochemical immunosensors for simultaneous detection of clinical biomarkers in complex fluids

SS Timilsina, M Ramasamy, N Durr… - Advanced …, 2022 - Wiley Online Library
Simultaneous detection of multiple disease biomarkers in unprocessed whole blood is
considered the gold standard for accurate clinical diagnosis. Here, this study reports the …