Evolutionary conservation of essential and highly expressed genes in Pseudomonas aeruginosa

A Dötsch, F Klawonn, M Jarek, M Scharfe, H Blöcker… - BMC genomics, 2010 - Springer
Background The constant increase in development and spread of bacterial resistance to
antibiotics poses a serious threat to human health. New sequencing technologies are now …

Comparative genomic analyses reveal core-genome-wide genes under positive selection and major regulatory hubs in outlier strains of Pseudomonas aeruginosa

U Sood, P Hira, R Kumar, A Bajaj, DLN Rao… - Frontiers in …, 2019 - frontiersin.org
Genomic information for outlier strains of Pseudomonas aeruginosa is exiguous when
compared with classical strains. We sequenced and constructed the complete genome of an …

Unveiling the microevolution of antimicrobial resistance in selected Pseudomonas aeruginosa isolates from Egyptian healthcare settings: A genomic approach

S Salem, NA Abdelsalam, AH Shata, SF Mouftah… - Scientific Reports, 2024 - nature.com
The incidence of Pseudomonas aeruginosa infections in healthcare environments,
particularly in low-and middle-income countries, is on the rise. The purpose of this study was …

Tracking the Origins of Pseudomonas aeruginosa Phylogroups by Diversity and Evolutionary Analysis of Important Pathogenic Marker Genes

SE Quiroz-Morales, S García-Reyes, GY Ponce-Soto… - Diversity, 2022 - mdpi.com
Pseudomonas aeruginosa is a widespread environmental bacterium and an opportunistic
pathogen that represents a health hazard due to its production of virulence factors and its …

[HTML][HTML] Detecting, mapping, and suppressing the spread of a decade-long Pseudomonas aeruginosa nosocomial outbreak with genomics

W Stribling, LR Hall, A Powell, C Harless, MJ Martin… - eLife, 2024 - elifesciences.org
Whole-genome sequencing is revolutionizing bacterial outbreak investigation but its
application to the clinic remains limited. In 2020, prospective and retrospective surveillance …

[HTML][HTML] A citywide, clonal outbreak of Pseudomonas aeruginosa

CJ Opperman, C Moodley, K Lennard, M Smith… - International Journal of …, 2022 - Elsevier
Background Outbreaks of community-acquired Pseudomonas aeruginosa are typically small
and localized. We investigated an increase in community-acquired infections with P …

Structural genome variants of Pseudomonas aeruginosa clone C and PA14 strains

J Klockgether, MM Pust, CF Davenport… - Frontiers in …, 2023 - frontiersin.org
Plasticity of Pseudomonas aeruginosa chromosomes is mainly driven by an extended
accessory genome that is shaped by insertion and deletion events. Further modification of …

The Pseudomonas aeruginosa Pan-Genome Provides New Insights on Its Population Structure, Horizontal Gene Transfer, and Pathogenicity

L Freschi, AT Vincent, J Jeukens… - Genome biology and …, 2019 - academic.oup.com
The huge increase in the availability of bacterial genomes led us to a point in which we can
investigate and query pan-genomes, for example, the full set of genes of a given bacterial …

New genotyping method discovers sustained nosocomial Pseudomonas aeruginosa outbreak in an intensive care burn unit

F Tissot, DS Blanc, P Basset, G Zanetti… - Journal of Hospital …, 2016 - Elsevier
Background Pseudomonas aeruginosa is a leading cause of healthcare-associated
infections in the intensive care unit (ICU). Aim To investigate an unexplained increase in the …

Diversity and Distribution of Resistance Markers in Pseudomonas aeruginosa International High-Risk Clones

B Kocsis, D Gulyás, D Szabó - Microorganisms, 2021 - mdpi.com
Pseudomonas aeruginosa high-risk clones are disseminated worldwide and they are
common causative agents of hospital-acquired infections. In this review, we will summarize …