Genomic islands 1 and 2 play key roles in the evolution of extensively drug-resistant ST235 isolates of Pseudomonas aeruginosa

P Roy Chowdhury, M Scott, P Worden… - Open …, 2016 - royalsocietypublishing.org
Pseudomonas aeruginosa are noscomially acquired, opportunistic pathogens that pose a
major threat to the health of burns patients and the immunocompromised. We sequenced …

Genomic heterogeneity underlies multidrug resistance in Pseudomonas aeruginosa: A population-level analysis beyond susceptibility testing

LJ Rojas, M Yasmin, J Benjamino, SM Marshall… - PloS one, 2022 - journals.plos.org
Background Pseudomonas aeruginosa is a persistent and difficult-to-treat pathogen in many
patients, especially those with Cystic Fibrosis (CF). Herein, we describe a longitudinal …

Population Structure of Clinical Pseudomonas aeruginosa from West and Central African Countries

P Cholley, R Ka, C Guyeux, M Thouverez… - PLoS …, 2014 - journals.plos.org
Background Pseudomonas aeruginosa (PA) has a non-clonal, epidemic population with a
few widely distributed and frequently encountered sequence types (STs) called 'high-risk …

[HTML][HTML] Genomic and phylogenomic characterization of carbapenem-resistant Pseudomonas aeruginosa 'high-risk'clone O4/ExoS+/ST654 circulating in Chilean …

A Opazo-Capurro, OA Aguilar-Vera… - Journal of Global …, 2024 - Elsevier
Abstract Introduction Carbapenem-resistant Pseudomonas aeruginosa (CRPA) is a serious
threat to public health. Globally, carbapenemases-producing CRPA isolates mainly belong …

Long-term Persistence of an Extensively Drug-Resistant Subclade of Globally Distributed Pseudomonas aeruginosa Clonal Complex 446 in an Academic Medical …

NB Pincus, KER Bachta, EA Ozer… - Clinical Infectious …, 2020 - academic.oup.com
Background Antimicrobial resistance (AMR) is a major challenge in the treatment of
infections caused by Pseudomonas aeruginosa. Highly drug-resistant infections are …

Analysis of a long-term outbreak of XDR Pseudomonas aeruginosa: a molecular epidemiological study

M Willmann, D Bezdan, L Zapata… - Journal of …, 2015 - academic.oup.com
Objectives Here we report on a long-term outbreak from 2009 to 2012 with an XDR
Pseudomonas aeruginosa on two wards at a university hospital in southern Germany …

Comparison of whole genome (wg-) and core genome (cg-) MLST (BioNumericsTM) versus SNP variant calling for epidemiological investigation of Pseudomonas …

DS Blanc, B Magalhães, I Koenig, L Senn… - Frontiers in …, 2020 - frontiersin.org
Whole genome sequencing (WGS) is increasingly used for epidemiological investigations of
pathogens. While SNP variant calling is currently considered as the most suitable method …

[PDF][PDF] Genomic diversity and virulence genes among clinical isolates of Pseudomonas aeruginosa

H Valadbeigi, RR Tabatabaei, A Malek, Z Sekawi… - Clin Lab, 2014 - core.ac.uk
Background: Typing of nosocomial pathogens is necessary to determine the source of an
outbreak. The aim was to determine the genomic variability among Pseudomonas …

[HTML][HTML] Molecular epidemiology of Pseudomonas aeruginosa in the intensive care units–a review

DS Blanc, P Francioli, G Zanetti - The open microbiology journal, 2007 - ncbi.nlm.nih.gov
Pseudomonas aeruginosa is one of the leading nosocomial pathogens in intensive care
units (ICU). This opportunist pathogen is commonly recovered from moist environments, and …

Phenotypic and genomic comparison of the two most common ExoU-positive Pseudomonas aeruginosa clones, PA14 and ST235

S Fischer, S Dethlefsen, J Klockgether, B Tümmler - Msystems, 2020 - Am Soc Microbiol
Genotyping of 2,882 Pseudomonas aeruginosa isolates that had been collected during the
last 40 years identified the ExoU-positive lineages PA14 (ST253) and ST235 as the second …